1. Gene
  2. CSN1S1 - casein alpha s1 Gene

CSN1S1 - casein alpha s1 Gene

中文名称:酪蛋白α s1

种属: Homo sapiens

同用名: CASA; CSN1

基因 ID: 1446 | 基因类型: protein coding

关于 CSN1S1

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:69,931,068-69,946,574 (from NCBI)

This gene has 6 transcripts (splice variants) and 54 orthologues. Restricted expression toward fat (RPKM 9.4).

功能概要

预测参与对脱氢表雄酮的反应;对雌二醇的反应;和对类固醇激素的反应。位于细胞外空间。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in response to dehydroepiandrosterone; response to estradiol; and response to steroid hormone. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

CSN1S1 基因产物(2)

mRNA Protein Name
NM_001025104.2 NP_001020275.1 alpha-S1-casein isoform 2 precursor
NM_001890.2 NP_001881.1 alpha-S1-casein isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alpha-S1-casein

casein, alpha

CSN1S1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属内
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
CSN1S1 P47710 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Milk Allergy

Milk Allergic Reaction

Milk Hypersensitivity

Allergy Milk

Food Allergy

Food Hypersensitivity

Food Allergies

Allergy Food

Food Allergen-Induced Hypersensitivity

Palmoplantar Keratoderma And Congenital Alopecia 2

Cataract-Alopecia-Sclerodactyly Syndrome

Cass

Autosomal Recessive Palmoplantar Keratoderma And Congenital Alopecia

PPKCA2

Autosomal Recessive Palmoplantar Hyperkeratosis And Congenital Alopecia

Palmoplantar Keratoderma And Congenital Alopecia, Wallis Type

Ppk-Ca, Wallis Type

Cataract, Alopecia, Sclerodactyly

Ppkca, Wallis Type

Ppkca Wallis Type

Cataract, Alopecia, Sclerodactyly Syndrome

Cow Milk Allergy

Bos Taurus Milk Allergy

Cow'S Milk Protein Sensitivity

Peanut Allergy

Allergy To Peanuts

Peanut Allergic Reaction

Allergies Peanut

Peanut Hypersensitivity

Lactose Intolerance

Lactose Malabsorption

Lm - Lactose Malabsorption

Alactasia

Dairy Product Intolerance

Hypolactasia

Milk Sugar Intolerance

Cow Milk Enteropathy

Intolerance Or Malabsorption Of Lactose

Lm - [Lactose Malabsorption]

Milk Intolerance

Goat Milk Allergy

Capra Hircus Milk Allergy

Interstitial Myocarditis
Perinatal Necrotizing Enterocolitis

Necrotizing Enterocolitis

Enterocolitis Necrotizing

Enterocolitis, Necrotizing

Necrotizing Enterocolitis In Fetus Or Newborn

Perinatal Necrotising Enterocolitis

Pseudomembranous Enterocolitis In Newborn

Nec

Mycetoma

Madura Foot

Mycetoma Of Foot

Dental Caries

Dental Caries Extending Into Pulp

Dental Caries Of Smooth Surface

Dental Caries Pit And Fissure

Smooth Surface Dental Caries

Dental Decay

Carious Teeth

Dental Cavity

Saprodontia

Teeth Decayed

Tooth Caries

Tooth Decay

Ige Responsiveness, Atopic

ATOPY

Atopy, Susceptibility To

Ige, Elevated Level Of

IGER

Immunoglobulin E, Basic Level Of, In Serum

Ige, Level Of

Igel

Ige Response Underlying Allergic Asthma And Rhinitis

Atopic Hypersensitivity

Immediate Hypersensitivity

Allergic Disease

Hypersensitivity

Allergic Hypersensitivity Disease

Allergic Condition

Allergic Reaction

Allergic Disposition

Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint

Mastitis

Breast Inflammation

Inflammatory Breast Disease

Inflammatory Disease Of Breast

Inflammation Of Non-Human Mammary Gland

Inflammatory Disorder Of Breast

Mastitis Nos

Acute Mastitis Nos

Acute Nonpuerperal Mastitis

Nonpuerperal Mastitis Nos

Subacute Mastitis Nos

Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Dyslexia
Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CSN1S1 VGNC VGNC:39664
Mus musculus CSN1S1 MGD MGI:88540
Bos taurus CSN1S1 VGNC VGNC:27763
Felis catus CSN1S1 VGNC VGNC:107322
Rattus norvegicus CSN1S1 RGD RGD:2430