2. Gene
  3. Pdpn - podoplanin Gene

Pdpn - podoplanin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: E11; T1a; Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha

基因 ID: 14726 | 基因类型: protein coding

关于 Pdpn

功能概要

Predicted to enable chaperone binding activity; chemokine binding activity; and signaling receptor binding activity. Involved in several processes, including lymph node development; lymphatic endothelial cell fate commitment; and positive regulation of platelet aggregation. Acts upstream of or within several processes, including lung alveolus development; lymphangiogenesis; and prostaglandin metabolic process. Located in several cellular components, including external side of plasma membrane; lamellipodium; and ruffle. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; hemolymphoid system; and reproductive system. Orthologous to human PDPN (podoplanin). [provided by Alliance of Genome Resources, Apr 2022]

Pdpn 基因产物(2)

mRNA Protein Name
NM_001290822.1 NP_001277751.1 podoplanin isoform 2 precursor
NM_010329.3 NP_034459.2 podoplanin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables amino acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
12032185 MGI
NOT enables folic acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
12032185 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17616532 MGI
NOT enables water channel activity IDA
IDA: 通过直接分析推断
9651190 MGI
NOT enables water transmembrane transporter activity IDA
IDA: 通过直接分析推断
9651190 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin-mediated cell contraction IDA
IDA: 通过直接分析推断
25341788 MGI
NOT involved in amino acid transport IDA
IDA: 通过直接分析推断
12032185 MGI
involved in cell migration IMP
IMP: 通过突变表型推断
10574709 MGI
acts upstream of or within cell population proliferation IMP
IMP: 通过突变表型推断
16869965 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
16869965 MGI
NOT involved in folic acid transport IDA
IDA: 通过直接分析推断
12032185 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
16869965 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
12654292 MGI
involved in lymph node development IMP
IMP: 通过突变表型推断
25347465 MGI
acts upstream of or within lymphangiogenesis IMP
IMP: 通过突变表型推断
12853470 MGI
involved in lymphatic endothelial cell fate commitment IMP
IMP: 通过突变表型推断
20110424 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
25347465 MGI
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
25347465 MGI
acts upstream of or within positive regulation of cell motility IMP
IMP: 通过突变表型推断
16869965 MGI
involved in positive regulation of platelet aggregation IDA
IDA: 通过直接分析推断
17616532 MGI
involved in positive regulation of platelet aggregation IMP
IMP: 通过突变表型推断
20110424 MGI
acts upstream of or within prostaglandin metabolic process IMP
IMP: 通过突变表型推断
16869965 MGI
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
16869965 MGI
involved in regulation of cell adhesion IMP
IMP: 通过突变表型推断
25347465 MGI
involved in regulation of myofibroblast contraction IMP
IMP: 通过突变表型推断
25347465 MGI
involved in regulation of substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
25347465 MGI
acts upstream of or within signal transduction IMP
IMP: 通过突变表型推断
16869965 MGI
NOT acts upstream of or within water transport IDA
IDA: 通过直接分析推断
9651190 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
23180825 MGI
located in filopodium IDA
IDA: 通过直接分析推断
10574709 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
10574709 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9632596 MGI
located in ruffle IDA
IDA: 通过直接分析推断
10574709 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

podoplanin

PA2.26 antigen

aggrus

glycoprotein 38

transmembrane glycoprotein E11

重组 Pdpn 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71219 Podoplanin Protein, Mouse (HEK293, Fc) Q62011 (G23-K133) ≥95%
HY-P73379 Podoplanin Protein, Mouse (sf9, His) Q62011 (M1-K133) ≥95%
HY-P73704 Podoplanin Protein, Mouse (HEK293, His-Fc) Q62011 (M1-L141) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70294 N-Acetylgalactosaminyltransferase 13 / 否
HY-RS10288 PDPN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdpn NCBI NCBI:10630
Rattus norvegicus Pdpn NCBI NCBI:54320
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z