2. Gene
  3. Pdpn - podoplanin Gene

Pdpn - podoplanin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: E11; Gp38; OTS-8; RTI40; T1-alpha

基因 ID: 54320 | 基因类型: protein coding

关于 Pdpn

功能概要

Predicted to enable chaperone binding activity; chemokine binding activity; and signaling receptor binding activity. Involved in several processes, including lung development; positive regulation of platelet activation; and response to hyperoxia. Acts upstream of or within cell adhesion; positive regulation of cell migration; and tube morphogenesis. Located in apical plasma membrane. Biomarker of adult respiratory distress syndrome; Bacterial pneumonia; nephrosis; and oligohydramnios. Orthologous to human PDPN (podoplanin). [provided by Alliance of Genome Resources, Apr 2022]

Pdpn 基因产物(1)

mRNA Protein Name
NM_019358.2 NP_062231.2 podoplanin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
12853470 RGD
involved in lung development IEP
IEP: 通过表达模式推断
8652186 RGD
involved in nervous system development IEP
IEP: 通过表达模式推断
8652186 RGD
acts upstream of or within positive regulation of cell migration IDA
IDA: 通过直接分析推断
12853470 RGD
involved in positive regulation of platelet activation IMP
IMP: 通过突变表型推断
16979138 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
12922978 RGD
acts upstream of or within tube morphogenesis IDA
IDA: 通过直接分析推断
12853470 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
7851650 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

podoplanin

E11 antigen epitope

RTI140

T1A

epithelial cell surface transmembrane protein antigen

glycoprotein 38

pulmonary type I alveolar epithelial cell transmembrane differentiation marker

type I cell 40 kDa protein

重组 Pdpn 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74624 Podoplanin Protein, Rat (HEK293, hFc) Q64294 (G23-L135) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70294 N-Acetylgalactosaminyltransferase 13 / 否
HY-RS10288 PDPN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdpn NCBI NCBI:10630
Mus musculus Pdpn NCBI NCBI:14726
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