2. Gene
  3. CIART - circadian associated repressor of transcription Gene

CIART - circadian associated repressor of transcription Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：昼夜节律相关的转录抑制因子

种属: Homo sapiens

同用名: GM129; CHRONO; C1orf51

基因 ID: 148523 | 基因类型: protein coding

关于 CIART

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,282,554-150,287,093 (from NCBI)

This gene has 7 transcripts (splice variants) and 216 orthologues. Broad expression in heart (RPKM 6.9), thyroid (RPKM 5.6) and 24 other tissues.

功能概要

预计启用电子邮箱绑定活动。预计参与基因表达的昼夜节律调节；运动节奏;和转录的负调控，DNA 模板。预测位于 PML 体内。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable E-box binding activity. Predicted to be involved in circadian regulation of gene expression; locomotor rhythm; and negative regulation of transcription, DNA-templated. Predicted to be located in PML body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CIART 基因产物(5)

mRNA Protein Name
NM_001300838.2 NP_001287767.1 circadian-associated transcriptional repressor isoform a
NM_001300839.2 NP_001287768.1 circadian-associated transcriptional repressor isoform b
NM_001300840.2 NP_001287769.1 circadian-associated transcriptional repressor isoform b
NM_001300841.2 NP_001287770.1 circadian-associated transcriptional repressor isoform b
NM_144697.4 NP_653298.1 circadian-associated transcriptional repressor isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24385426 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

circadian-associated transcriptional repressor

chIP-derived repressor of network oscillator

CIART 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
CIART Q8N365 Bmal1 Mus musculus Q9WTL8
Anti Tag CoIP
24737000
种属内
CIART Q8N365 DAB1 Homo sapiens O75553
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Gallbladder Benign Neoplasm
Gallbladder Adenoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02705 CIART Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CIART VGNC VGNC:27358
Felis catus CIART VGNC VGNC:60897
Macaca mulatta CIART VGNC VGNC:71345
Rattus norvegicus CIART RGD RGD:1566380
Mus musculus CIART MGD MGI:2684975
Canis familiaris CIART VGNC VGNC:39265
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