CTF1 - cardiotrophin 1 Gene

中文名称：心肌营养素 1

种属: Homo sapiens

同用名: CT1; CT-1

基因 ID: 1489 | 基因类型: protein coding

关于 CTF1

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:30,895,846-30,903,560 (from NCBI)

This gene has 2 transcripts (splice variants), 88 orthologues and 1 paralogue. Broad expression in ovary (RPKM 6.4), heart (RPKM 3.8) and 20 other tissues.

功能概要

该基因编码的蛋白质是一种分泌性细胞因子，可在体外诱导心肌细胞肥大。它已被证明可以结合并激活 ILST/gp130 受体。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2008 年 12 月]

The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

CTF1 基因产物(2)

mRNA	Protein	Name
NM_001142544.3	NP_001136016.1	cardiotrophin-1 isoform 2
NM_001330.5	NP_001321.1	cardiotrophin-1 isoform 1

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of tyrosine phosphorylation of STAT protein	IDA IDA: 通过直接分析推断	21912637	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

cardiotrophin-1

cardiophin 1

重组 CTF1 蛋白

目录号	产品名	蛋白编号	纯度
HY-P7149	Cardiotrophin-1/CTF1 Protein, Human (CHO)	Q16619 (S2-A201)	≥95%
HY-P7739	Cardiotrophin-1/CTF1 Protein, Human (His)	Q16619 (M1-A201)	≥95%
HY-P72870	Cardiotrophin-1/CTF1 Protein, Human (HEK293)	Q16619 (S2-A201)	≥95%
HY-P72871	Cardiotrophin-1/CTF1 Protein, Human (HEK293, Fc)	Q16619 (S2-A201)	≥95%

关联疾病

疾病名称

别名

Leukemia

Leukemias	Leukaemia, Unspecified, Without Mention Of Remission
Aleukemic Leukaemia	Chronic Leukaemia
Subacute Leukaemia	Leukaemia Disorder
Leukaemia Nos

Heart Valve Disease

Heart Valve Diseases	Valvular Heart Disease
Valvular Heart Diseases	Heart Valve Prolapse

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Motor Neuron Disease

Anterior Horn Cell Disease	Motor Neuron Diseases
Mnd - [Motor Neurone Disease]	Lou Gehrig Disease
Creeping Palsy	Creeping Paralysis
Bulbar Motor Neuron Disease	Bulbar Syndrome
Anterior Horn Cell Disorder	Hereditary Motor Neuron Disease

Heart Disease

Heart Failure	Congenital Heart Disease
Heart Diseases	Congenital Heart Defects
Congenital Heart Defect	Heart Malformation
Congenital Anomaly Of Heart	Heart Defect
Heart-Congenital Defect	Congenital Heart Disorder
Heart Defects Congenital	Heart Defects, Congenital
Heart Defects	Heart Disease, Congenital
Disease, Heart, Congenital	Congestive Heart Failure

Myocardial Infarction

Heart Attack	Myocardial Infarction, Susceptibility To
Myocardial Infarction 1	Myocardial Infarction, Protection Against
Myocardial Infarction, Decreased Susceptibility To	Myocardial Infarction, Decreased
Myocardial Infarct	MCI1
Premature Myocardial Infarction	Myocardial Infarction, Susceptibility To, Type 1

Hypertensive Heart Disease

Crisponi/Cold-Induced Sweating Syndrome 2

Cold-Induced Sweating Syndrome 2	CISS2
Sweating Syndrome, Cold-Induced, Type 2

Cold-Induced Sweating Syndrome

Crisponi Syndrome	Sohar-Crisponi Syndrome
Ciss	Cntf Receptor-Related Disorders
Muscle Contractions, Tetanoform, With Characteristic Face, Camptodactyly, Hyperthermia, And Sudden Death	Sweating Syndrome, Cold-Induced

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03295	CTF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	CTF1	VGNC	VGNC:99505
Bos taurus	CTF1	VGNC	VGNC:27793
Rattus norvegicus	CTF1	RGD	RGD:2442
Mus musculus	CTF1	MGD	MGI:105115
Canis familiaris	CTF1	VGNC	VGNC:54015
Others	CTF1	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CTF1 - cardiotrophin 1 Gene

关于 CTF1

功能概要

CTF1 基因产物(2)

重组 CTF1 蛋白

关联疾病

直系同源

热门区域

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CTF1 - cardiotrophin 1 Gene

关于 CTF1

功能概要

CTF1 基因产物(2)

重组 CTF1 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z