CYBB - cytochrome b-245 beta chain Gene

中文名称：细胞色素 b-245 β 链

种属: Homo sapiens

同用名: CGD; CGDX; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX

基因 ID: 1536 | 基因类型: protein coding

关于 CYBB

Cytogenetic location: Xp21.1-p11.4 Genomic coordinates (GRCh38): X:37,780,059-37,813,461 (from NCBI)

This gene has 6 transcripts (splice variants), 210 orthologues, 6 paralogues and is associated with 5 phenotypes. Broad expression in appendix (RPKM 106.7), bone marrow (RPKM 63.5) and 15 other tissues.

功能概要

细胞色素 b (-245) 由细胞色素 b α (CYBA) 和β (CYBB) 链组成。它已被提议作为吞噬细胞的杀菌氧化酶系统的主要成分。 CYBB 缺陷是与慢性肉芽肿病 (CGD) 相关的五种生化缺陷之一。在这种疾病中，吞噬细胞 NADPH 氧化酶的活性降低；中性粒细胞能够吞噬细菌，但不能在吞噬泡中杀死它们。致死缺陷的原因是无法增加细胞的呼吸，因此无法将活性氧输送到吞噬液泡中。[RefSeq 提供，2008 年 7 月]

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]

CYBB 基因产物(2)

mRNA	Protein	Name
XM_047441855.1	XP_047297811.1	cytochrome b-245 heavy chain isoform X1
NM_000397.4	NP_000388.2	cytochrome b-245 heavy chain

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
contributes to electron transfer activity	IDA IDA: 通过直接分析推断	12042318	GOA
enables flavin adenine dinucleotide binding	IMP IMP: 通过突变表型推断	9774399	GOA
enables heme binding	IMP IMP: 通过突变表型推断	9774399	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	3305576	GOA
enables protein heterodimerization activity	IPI IPI: 通过物理相互作用推断	12042318	GOA
contributes to superoxide-generating NAD(P)H oxidase activity	IDA IDA: 通过直接分析推断	12042318	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in innate immune response	IMP IMP: 通过突变表型推断	9774399	GOA
involved in respiratory burst	IMP IMP: 通过突变表型推断	9774399	GOA
involved in superoxide anion generation	IDA IDA: 通过直接分析推断	12042318	GOA
involved in superoxide metabolic process	IDA IDA: 通过直接分析推断	12042318	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of NADPH oxidase complex	IDA IDA: 通过直接分析推断	3305576	GOA
located in plasma membrane	IDA IDA: 通过直接分析推断	15233623	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CYBB 蛋白结构

Ferric_reduct

FAD_binding_8

NAD_binding_6

0
100
200
300
400
500
570 a.a.

蛋白主名

其他名称

cytochrome b-245 heavy chain

CGD91-phox	NADPH oxidase 2
cytochrome b(558) subunit beta	cytochrome b-245 beta polypeptide
cytochrome b558 subunit beta	heme-binding membrane glycoprotein gp91phox
neutrophil cytochrome b 91 kDa polypeptide	p22 phagocyte B-cytochrome
superoxide-generating NADPH oxidase heavy chain subunit

CYBB 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CYBB	P04839	CYBC1	Homo sapiens	Q9BQA9	Y2H Prey Pooling	32296183
种属内	CYBB	P04839	CYBC1	Homo sapiens	Q9BQA9	Validated Y2H	32296183
种属内	CYBB	P04839	CYBC1	Homo sapiens	Q9BQA9	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CYBB 蛋白

目录号	产品名	蛋白编号	纯度
HY-P72161	CYBB/Nox2 Protein, Human (His)	P04839 (E283-F570)	≥95%

CYBB 抗体

目录号	产品名	应用	反应物种
HY-P81195	NOX2 Antibody	WB, ELISA, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat

关联疾病

疾病名称

别名

Malaria

Malaria, Susceptibility To	Malaria, Resistance To
Malaria, Cerebral	Cerebral Malaria
Malaria, Severe, Susceptibility To	Malaria, Severe, Resistance To
Malaria, Cerebral, Susceptibility To	Induced Malaria
Malaria, Vivax, Protection Against	Malaria, Severe
Malaria, Cerebral, Reduced Risk Of	Malaria, Protection Against
Resistance To Malaria Due To G6pd Deficiency	Malaria Due To G6pd Deficiency
Malarial Encephalitis	CM
Malaria Cerebral	Susceptibility To Malaria
Acute Pernicious Fever	Aestivo-Autumnal Fever
Aestivo Autumnal Malaria	Chagres Fever
Continued Malaria Fever	Estivo-Autumnal Fever
Estivo-Autumnal Malaria	Estivo-Autumnal Malarial Fever
Falciparum Fever	Malignant Tertian Fever
Malignant Tertian Malaria	Pernicious Intermittent Fever
Pernicious Malaria	Quotidian Malaria
Subtertian Fever	Subtertian Malaria Fever
Subtertian Malignant Tertian Malaria	Tropical Malaria
Algid Malaria	Bilious Haemoglobinuric Fever
Black Water Fever	Blackwater Fever
Malarial Blackwater Fever	Severe Malarial Falciparum
West African Fever	Malarial Haematinuria
Haemoglobinuric Fever	Haemoglobinuric Malaria
Severe Plasmodium Falciparum Malaria	Malarial Haemoglobinuria
Malarial Haematuria	Falciparum Malaria [Malignant Tertian]
Malaria Tropica	Malarial Shock
Chagres Virus Disease	Malignant Malaria
Mtm - [Malignant Tertian Malaria]	Tm -[Malignant Tertian Malaria]
Panama Fever	St - [Subtertian Malaria]
Malarial Quotidian	Benign Tertian Malaria
Tertian Ague	Vivax Fever
Plasmodium Vivax Malaria Nos	Btm - [Benign Tertian Malaria]
Bt - [Benign Tertian Malaria]	Vivax Malaria
Benign Tertian Vivax Malaria	Tertian Malaria
Quartan Malaria	Quartan Ague
Quartan Fever	Plasmodium Malariae Malaria Nos
Quartan Malarial	Malaria By Plasmodium Malariae
Malariae Malaria	Ovale Tertian Malaria
Plasmodium Ovale Fever	Malaria Fever By Plasmodium Ovale
Ovale Malaria	Malaria By Plasmodium Ovale
Malarial Ovale	Marsh Fever
Remittent Congestive Fever	Coastal Fever
Remittent Gastric Fever	Miasmatic Fever
Congestive Remittent Fever	Intermittent Fever
Jungle Fever	Paludism
Cameroon Fever	Ague
Corsican Fever	Intermittent Bilious Fever
Disease Due To Plasmodiidae	Malarial Fever
Plasmodiosis	Remittent Fever
Roman Fever	Malaria Fever Nos
Malaria Nos	Paludal Fever
Clinically Diagnosed Malaria	Clinically Diagnosed Malaria Without Parasitological Confirmation
Congestive Fever	Malarial Cachexia
Marsh Cachexia	Paludal Cachexia
Recurrent Malaria	Remittent Malaria

Hypertension, Essential

Essential Hypertension	Hypertension
High Blood Pressure	Hypertension, Essential, Susceptibility To
Hypertensive Disease	Primary Hypertension
EHT	Hypertension, Salt-Sensitive Essential, Susceptibility To
Hyperpiesia	Idiopathic Hypertension
Hypertensive Disorder	Hypertension, Essential, Susceptibility To, 3
Hypertension, Essential 3	Hypertension, Essential, Salt-Sensitive
Hypertension, Essential, Susceptibility To, 6	Hypertension, Essential 6
Hypertension, Salt-Sensitive Essential	Hypertension, Susceptibility To
Hypertension, Essential, Susceptibility To, 4	Hypertension, Essential 4
Hypertension, Essential, Susceptibility To, 2	Hypertension, Essential 2
Hypertension, Essential, Susceptibility To, 1	Hypertension, Essential 1
Hypertension, Essential, Susceptibility To, 5	Hypertension, Essential 5
Htn	Vascular Hypertensive Disorder
Systemic Primary Arterial Hypertension	Hbp - [High Blood Pressure]
Systemic Arterial Hypertensive Disorder	Elevated Blood Pressure
Arterial Hypertension Nos	Hypertension Nos
Benign Hypertension	Systemic Arterial Hypertension
Systemic Hypertension	Artery Htn
Benign Htn	Vascular Htn
Vascular Hypertension	Cholesterol Hypertension
Cholesterol Htn	Idiopathic Htn
Malignant Hypertension	Malignant Htn
Raised Blood Pressure	Cardiovascular Hypertension
Primary Htn - [Hypertension]	High Arterial Tension
High Blood Pressure Disorder	Ht - [Hypertension]
Htn - [Hypertension]	Hypertensive Vascular Disease
Hypertensive Vascular Degeneration

Splenic Abscess

Tuberculous Salpingitis

Granulomatous Disease, Chronic, Autosomal Recessive, 1

Chronic Granulomatous Disease Due To Deficiency Of Ncf-1	CGD1
Ncf1 Deficiency	Soluble Oxidase Component Ii Deficiency
Soc2 Deficiency	P47-Phox Deficiency
Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type I	Deficiency Of Neutrophil Cytosol Factor 1
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 1	Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I
Cgd, Autosomal Recessive Cytochrome B-Positive, Type I	Granulomatous Disease, Chronic, Due To Ncf1 Deficiency
Neutrophil Cytosol Factor 1 Deficiency	Chronic Granulomatous Disease 1, Autosomal Recessive
Autosomal Recessive Chronic Granulomatous Disease 1	Cdg1
Deficiency Of Ncf1	Deficiency Of P47-Phox
Deficiency Of Soc2	Deficiency Of Soluble Oxidase Component Ii
Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type I	Chronic Granulomatous Disease Due To Ncf1 Deficiency

Phagocyte Bactericidal Dysfunction

Phagocytic Dysfunction

Gastrointestinal Tularemia

Enteric Tularemia

Intestinal Tularaemia

Immunodeficiency 55

Combined Immunodeficiency Due To Gins1 Deficiency	IMD55
Cid Due To Gins1 Deficiency	Combined Immunodeficiency With Intrauterine Growth Retardation-Nk Cell Deficiency-Neutropenia
Combined Immunodeficiency With Intrauterine Growth Retardation-Natural Killer Cell Deficiency-Neutropenia

Ehrlichiosis

Human Ehrlichiosis	He
Hey

Immunodeficiency 27b

Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency	IMD27B
Immunodeficiency 27b, Mycobacteriosis, Autosomal Dominant	Ifngr1 Deficiency, Autosomal Dominant
Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency	Autosomal Dominant Msmd Due To Partial Ifngammar1 Deficiency
Autosomal Dominant Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency	Immunodeficiency 27b, Mycobacteriosis, Ad
Autosomal Dominant Ifngr1 Deficiency	Autosomal Dominant Immunodeficiency 27b, Mycobacteriosis
Immunodeficiency, Type 27b, Mycobacteriosis, Autosomal Dominant

Ectodermal Dysplasia

Congenital Ectodermal Defect	Congenital Ectodermal Dysplasia
Ectodermal Dysplasia Syndrome	Dysplasia, Ectodermal

Suppurative Lymphadenitis

Suppurative Lymphadenopathy

Granulomatous Disease, Chronic, Autosomal Recessive, 4

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Negative	Cyba Deficiency
CGD4	Cgd Due To Deficiency Of The Alpha Subunit Of Cytochrome B
Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Negative	Cgd, Autosomal Recessive Cytochrome B-Negative
Chronic Granulomatous Disease 4, Autosomal Recessive	Autosomal Recessive Chronic Granulomatous Disease 4
Autosomal Recessive Cytochrome B-Negative Cgd	Chronic Granulomatous Disease Due To Deficiency Of Cyba
Cgd Due To Deficiency Of Alpha Subunit Of Cytochrome B	Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Negative
Granulomatous Disease, Chronic, Cytochrome-B-Negative, Autosomal Recessive

Renal Hypertension

Hypertension Renal

Hypertension, Renal

X-Linked Recessive Disease

Myocardial Infarction

Heart Attack	Myocardial Infarction, Susceptibility To
Myocardial Infarction 1	Myocardial Infarction, Protection Against
Myocardial Infarction, Decreased Susceptibility To	Myocardial Infarction, Decreased
Myocardial Infarct	MCI1
Premature Myocardial Infarction	Myocardial Infarction, Susceptibility To, Type 1

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency Disease
Primary Immunodeficiency	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease	Coronary Artery Disease, Susceptibility To
Coronary Artery Anomaly	Myocardial Ischemia
Congenital Anomaly Of Coronary Artery	Coronary Arteriosclerosis
Coronary Disease	Coronary Heart Disease
Coronary Artery Disorder	LPAQTL
Lpa Deficiency, Congenital	Coronary Artery Abnormality
Coronary Artery Anomaly, Congenital	Chd
Coronary Syndrome	Congenital Malformations Of Coronary Vessels
Malformation Of Coronary Vessels	Congenital Coronary Artery Anomaly
Congenital Coronary Artery Deformity	Congenital Coronary Artery Disorder
Abnormal Coronary Artery	Congenital Coronary Artery Malposition
Congenital Coronary Disease	Congenital Anomaly Of Coronary Arteries

Leukocyte Adhesion Deficiency, Type I

Leukocyte Adhesion Deficiency	Leukocyte Adhesion Deficiency 1
LAD1	Lad
Leukocyte Adhesion Deficiency Type 1	Lymphocyte Function-Associated Antigen 1 Immunodeficiency
Leukocyte Adhesion Deficiency Type I	Linear Iga Bullous Dermatosis
Linear Iga Dermatosis	Leukocyte-Adhesion Deficiency Syndrome
Lfa1 Immunodeficiency	Congenital Leukocyte Adherence Deficiency
Lad-I	Linear Iga Disease
Leukocyte Adhesion Deficiency Syndrome	Lad 1
Lfa 1 Immunodeficiency	Linear Immunoglobulin A Dermatosis
Leucocyte Adhesion Deficiency Type 1	Leukocyte Adhesion Molecule Deficiency Type 1

Granulomatous Disease, Chronic, Autosomal Recessive, 2

Chronic Granulomatous Disease Due To Deficiency Of Ncf-2	CGD2
Ncf2 Deficiency	P67-Phox Deficiency
Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type Ii	Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 2
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Ii	Cgd, Autosomal Recessive Cytochrome B-Positive, Type Ii
Granulomatous Disease, Chronic, Due To Ncf2 Deficiency	Neutrophil Cytosol Factor 2 Deficiency
Chronic Granulomatous Disease 2, Autosomal Recessive	Autosomal Recessive Chronic Granulomatous Disease 2
Cdg2	Deficiency Of Ncf2
Deficiency Of P67-Phox	Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type Ii
Deficiency Of Neutrophil Cytosol Factor 2	Avellino Corneal Dystrophy

Middle Ear Adenocarcinoma

Adenocarcinoma Of Middle Ear

Adenocarcinoma Of The Middle Ear

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

Human Granulocytic Anaplasmosis

Human Granulocytic Ehrlichiosis	Hge
Human Ehrlichial Infection, Human Granulocytic Type	Human Anaplasmosis Due To Anaplasma Phagocytophilum

Cervical Adenitis

Cervical Lymphadenitis

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Diabetes Mellitus, Non-Insulin-Dependent	Type 2 Diabetes
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Skin Disease

Skin Diseases	Abnormality Of The Skin
Skin Diseases, Genetic	Genodermatosis
Skin And Subcutaneous Tissue Disease	Dermatologic Disorders

Renovascular Hypertension

Hypertension, Renovascular

Hypertension Renovascular

Granulomatous Disease, Chronic, X-Linked

CGDX	Chronic Granulomatous Disease, X-Linked
X-Linked Chronic Granulomatous Disease	Cgd
Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked	Cdgx
X-Linked Chronic Cytochrome B-Negative Granulomatous Disease	Chronic Granulomatous Disease Cytochrome B-Negative X-Linked
Chronic Granulomatous Disease Cytochrome B-Positive X-Linked	Granulomatous Disease, Chronic, X-Linked, Variant

Chronic Granulomatous Disease

Cgd	Granulomatous Disease, Chronic
Autosomal Recessive Chronic Granulomatous Disease	X-Linked Chronic Granulomatous Disease
Bridges-Good Syndrome	Congenital Dysphagocytosis
Quie Syndrome	Chronic Septic Granulomatosis
Chronic Granulomatous Disorder	Granulomatous Disease Chronic
Granulomatous Disease, Chronic, X-Linked

Nervous System Disease

Abnormality Of The Nervous System	Nervous System Diseases
Nervous System Disorder

Immunodeficiency 34

Atypical Mycobacteriosis, Familial, X-Linked 2	X-Linked Mendelian Susceptibility To Mycobacterial Diseases Due To Cybb Deficiency
IMD34	Amcbx2
Immunodeficiency 34, Mycobacteriosis, X-Linked	X-Linked Msmd Due To Cybb Deficiency
Familial Atypical Mycobacteriosis X-Linked 2	Familial, X-Linked, Atypical Mycobacteriosis 2
Familial Disseminated Atypical Mycobacterial Infection X-Linked 2	Mendelian Susceptibility To Mycobacterial Disease X-Linked 2
X-Linked Immunodeficiency 34, Mycobacteriosis	Immunodeficiency, Type 34, Mycobacteriosis, X-Linked

Vascular Disease

Vascular Diseases	Aneurysm
Spinal Cord Ischemia	Spinal Cord Vascular Diseases
Vascular Tissue Disease	Vascular Anomaly

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03423	CYBB Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS03424	Cybb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS03425	Cybb Rat Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	CYBB	VGNC	VGNC:71576
Canis familiaris	CYBB	VGNC	VGNC:50285
Felis catus	CYBB	VGNC	VGNC:61313
Bos taurus	CYBB	VGNC	VGNC:50265
Mus musculus	CYBB	MGD	MGI:88574
Rattus norvegicus	CYBB	RGD	RGD:620574
Others	CYBB	NCBI

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CYBB - cytochrome b-245 beta chain Gene

关于 CYBB

功能概要

CYBB 基因产物(2)

CYBB 蛋白结构

CYBB 蛋白互作信息

重组 CYBB 蛋白

CYBB 抗体

关联疾病

直系同源

热门区域

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CYBB - cytochrome b-245 beta chain Gene

关于 CYBB

功能概要

CYBB 基因产物(2)

CYBB 蛋白结构

CYBB 蛋白互作信息

重组 CYBB 蛋白

CYBB 抗体

关联疾病

相关产品

直系同源

热门区域

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C

F

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