2. Gene
  3. Hoxa9 - homeobox A9 Gene

Hoxa9 - homeobox A9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D6a9; Hox-1.7

基因 ID: 15405 | 基因类型: protein coding

关于 Hoxa9

功能概要

This gene is located in a cluster of developmentally and temporally regulated genes on chromosome 6 encoding proteins involved in pattern formation. These proteins contain a characteristic DNA-binding motif called a homeodomain and function in transcriptional regulation. There are four distinct clusters of similar genes on chromosomes 2, 6, 11, and 15. The protein encoded by this gene is important for hematopoeisis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Hoxa9 基因产物(2)

mRNA Protein Name
NM_001277238.1 NP_001264167.1 homeobox protein Hox-A9 isoform 2
NM_010456.3 NP_034586.1 homeobox protein Hox-A9 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17327400 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
10082572 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9343407 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior pattern specification IGI
IGI: 通过遗传相互作用推断
8625797 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
8625797 MGI
acts upstream of or within definitive hemopoiesis IGI
IGI: 通过遗传相互作用推断
17761289 MGI
acts upstream of or within embryonic forelimb morphogenesis IGI
IGI: 通过遗传相互作用推断
8625797 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
8625797 MGI
acts upstream of or within embryonic skeletal system development IMP
IMP: 通过突变表型推断
8625797 MGI
acts upstream of or within male gonad development IGI
IGI: 通过遗传相互作用推断
23760953 MGI
acts upstream of or within mammary gland development IGI
IGI: 通过遗传相互作用推断
9892669 MGI
involved in negative regulation of myeloid cell differentiation IDA
IDA: 通过直接分析推断
11438208 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17327400 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17327400 MGI
acts upstream of or within proximal/distal pattern formation IGI
IGI: 通过遗传相互作用推断
8625797 MGI
acts upstream of or within regulation of gene expression IGI
IGI: 通过遗传相互作用推断
23760953 MGI
acts upstream of or within single fertilization IGI
IGI: 通过遗传相互作用推断
23760953 MGI
acts upstream of or within spermatogenesis IGI
IGI: 通过遗传相互作用推断
23760953 MGI
acts upstream of or within uterus development IGI
IGI: 通过遗传相互作用推断
23760953 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription regulator complex IDA
IDA: 通过直接分析推断
9343407 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homeobox protein Hox-A9

homeo box A9

homeobox protein Hox-1.7

Hoxa9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Hoxa9 P09631 Pbx1 Mus musculus P41778
Y2H Array
20211142
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108350 MI-2-2 Inhibitor 99.92% 否
HY-100688 ML390 Inhibitor 99.72% 否
HY-122623 DB818 Inducer 98.36% 否
HY-141716 SW2_110A Inhibitor 99.19% 否
HY-101520A Dot1L-IN-1 TFA Inhibitor 98.56% 否
HY-122623A DB818 dihydrochloride Inducer / 否
HY-122698 CCI-007 Activator 98.45% 否
HY-155526 FY-21 Inhibitor / 否
HY-RS06303 HOXA9 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-101520 Dot1L-IN-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hoxa9 NCBI NCBI:3205
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