2. Gene
  3. Hpn - hepsin Gene

Hpn - hepsin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hlb320

基因 ID: 15451 | 基因类型: protein coding

关于 Hpn

功能概要

This gene encodes a type II transmembrane serine Protease that may function in diverse processes, including regulation of cell growth. Deficiency in this gene results in hearing loss. The protein is cleaved into a catalytic serine Protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

Hpn 基因产物(3)

mRNA Protein Name
NM_001110252.2 NP_001103722.1 serine protease hepsin isoform 1 precursor
NM_001276269.1 NP_001263198.1 serine protease hepsin isoform 3 precursor
NM_008281.4 NP_032307.2 serine protease hepsin isoform 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
22912808 MGI
involved in cochlea morphogenesis IMP
IMP: 通过突变表型推断
20683358 MGI
involved in detection of mechanical stimulus involved in sensory perception of sound IMP
IMP: 通过突变表型推断
17620368 MGI
involved in epithelium development IEP
IEP: 通过表达模式推断
8346233 MGI
acts upstream of or within negative regulation of alkaline phosphatase activity IMP
IMP: 通过突变表型推断
22912808 MGI
involved in pilomotor reflex IMP
IMP: 通过突变表型推断
17620368 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
17620368 MGI
involved in positive regulation of thyroid hormone generation IMP
IMP: 通过突变表型推断
17620368 MGI
involved in potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
17620368 MGI
involved in response to thyroid hormone IMP
IMP: 通过突变表型推断
20683358 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
22912808 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IMP
IMP: 通过突变表型推断
17620368 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
17918732 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12744720 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine protease hepsin

重组 Hpn 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77961 Hepsin/HPN Protein, Mouse (HEK293, His) O35453 (T60-P436) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B2087 Glycerol phenylbutyrate 99.81% 是
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135366 HPN-01 Inhibitor 98.61% 否
HY-RS06342 HPN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hpn NCBI NCBI:3249
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z