2. Gene
  3. DAPK3 - death associated protein kinase 3 Gene

DAPK3 - death associated protein kinase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：死亡相关蛋白激酶 3

种属: Homo sapiens

同用名: DLK; ZIP; ZIPK

基因 ID: 1613 | 基因类型: protein coding

关于 DAPK3

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:3,958,453-3,971,099 (from NCBI)

This gene has 7 transcripts (splice variants), 152 orthologues and 4 paralogues. Ubiquitous expression in endometrium (RPKM 16.5), prostate (RPKM 15.3) and 25 other tissues.

功能概要

死亡相关蛋白激酶 3 (DAPK3) 在哺乳动物细胞中过表达时会诱导细胞凋亡的形态学变化。这些结果表明 DAPK3 可能在诱导细胞凋亡中发挥作用。[RefSeq 提供，2008 年 7 月]

Death-associated protein kinase 3 (DAPK3) induces morphological changes in Apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of Apoptosis. [provided by RefSeq, Jul 2008]

DAPK3 基因产物(2)

mRNA Protein Name
NM_001348.3 NP_001339.1 death-associated protein kinase 3
NM_001375658.1 NP_001362587.1 death-associated protein kinase 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
10356987 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18239682 GOA
enables leucine zipper domain binding IPI
IPI: 通过物理相互作用推断
10580117 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15292222 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
18239682 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
10356987 GOA
enables small GTPase binding IDA
IDA: 通过直接分析推断
23454120 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apoptotic process IDA
IDA: 通过直接分析推断
10580117 GOA
involved in apoptotic process IMP
IMP: 通过突变表型推断
12917339 GOA
involved in cellular response to type II interferon IDA
IDA: 通过直接分析推断
18995835 GOA
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
10356987 GOA
involved in negative regulation of translation IDA
IDA: 通过直接分析推断
18995835 GOA
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
21487036 GOA
involved in positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
21454679 GOA
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
18239682 GOA
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
10356987 GOA
involved in regulation of actin cytoskeleton organization IDA
IDA: 通过直接分析推断
23454120 GOA
involved in regulation of focal adhesion assembly IDA
IDA: 通过直接分析推断
23454120 GOA
involved in regulation of mitotic cell cycle IMP
IMP: 通过突变表型推断
21487036 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DAPK3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (13 - 275)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 454 a.a.
蛋白主名 其他名称

death-associated protein kinase 3

DAP kinase 3

重组 DAPK3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77286 DAPK3/ZIPK Protein, Human (sf9, GST) O43293-1 (M1-R454) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15513 TC-DAPK 6 Inhibitor 98.26% 否
HY-15847 HS38 Inhibitor ≥99.0% 否
HY-117364 HS148 Inhibitor 95.50% 否
HY-123983 HS56 Inhibitor / 否
HY-RS03529 DAPK3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-120040 HS94 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus DAPK3 VGNC VGNC:61338
Bos taurus DAPK3 VGNC VGNC:27878
Mus musculus DAPK3 MGD MGI:1203520
Macaca mulatta DAPK3 VGNC VGNC:71734
Rattus norvegicus DAPK3 RGD RGD:621766
Canis familiaris DAPK3 VGNC VGNC:39771
Others DAPK3 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z