1. Gene
  2. Il10rb - interleukin 10 receptor, beta Gene

Il10rb - interleukin 10 receptor, beta Gene

种属: Mus musculus

同用名: Crfb4; CRF2-4; Il10r2; D21S58h; IL-10R2; D16H21S58; 6620401D04Rik

基因 ID: 16155 | 基因类型: protein coding

关于 Il10rb

功能概要

Enables interleukin-10 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway; positive regulation of cellular respiration; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within defense response to virus. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis B and inflammatory bowel disease 25. Orthologous to human IL10RB (interleukin 10 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Il10rb 基因产物(5)

mRNA Protein Name
NM_001405058.1 NP_001391987.1 interleukin-10 receptor subunit beta isoform 2
NM_001405059.1 NP_001391988.1 interleukin-10 receptor subunit beta isoform 3 precursor
NM_001405060.1 NP_001391989.1 interleukin-10 receptor subunit beta isoform 4
NM_001405062.1 NP_001391991.1 interleukin-10 receptor subunit beta isoform 5 precursor
NM_008349.6 NP_032375.2 interleukin-10 receptor subunit beta isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-10 receptor activity IMP
IMP: 通过突变表型推断
9463407 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11416224 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-10 receptor subunit beta

IL-10 receptor subunit beta

IL-10R subunit 2

IL-10R subunit beta

IL-10RB

cytokine receptor class-II member 4

cytokine receptor family 2 member 4

cytokine receptor family II, member 4

interleukin 10 receptor 2

interleukin-10 receptor subunit 2

重组 Il10rb 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74837 IL-10R beta Protein, Mouse (HEK293, His) Q8VHM7 (M22-S222) ≥95%
HY-P74838 IL-10R beta Protein, Mouse (HEK293, hFc) Q8VHM7 (M22-S222) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il10rb NCBI NCBI:3588