2. Gene
  3. Il17ra - interleukin 17 receptor A Gene

Il17ra - interleukin 17 receptor A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Il17r; Cdw217; VDw217

基因 ID: 16172 | 基因类型: protein coding

关于 Il17ra

功能概要

Enables interleukin-17 receptor activity and signaling receptor binding activity. Involved in several processes, including granulocyte chemotaxis; interleukin-17-mediated signaling pathway; and positive regulation of cytokine production involved in inflammatory response. Acts upstream of or within positive regulation of interleukin-13 production and positive regulation of interleukin-5 production. Located in plasma membrane. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in immunodeficiency 51. Orthologous to human IL17RA (interleukin 17 receptor A). [provided by Alliance of Genome Resources, Apr 2022]

Il17ra 基因产物(1)

mRNA Protein Name
NM_008359.2 NP_032385.1 interleukin-17 receptor A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-17 receptor activity IDA
IDA: 通过直接分析推断
33723527 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19825828 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
20554964 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T-helper 17 type immune response IDA
IDA: 通过直接分析推断
28561022 MGI
involved in defense response to fungus IMP
IMP: 通过突变表型推断
20554964 MGI
involved in granulocyte chemotaxis IMP
IMP: 通过突变表型推断
20554964 MGI
involved in interleukin-17-mediated signaling pathway IDA
IDA: 通过直接分析推断
19825828 MGI
involved in positive regulation of cytokine production involved in inflammatory response IDA
IDA: 通过直接分析推断
33723527 MGI
acts upstream of or within positive regulation of cytokine production involved in inflammatory response IGI
IGI: 通过遗传相互作用推断
16785495 MGI
involved in positive regulation of inflammatory response IDA
IDA: 通过直接分析推断
33723527 MGI
acts upstream of or within positive regulation of inflammatory response IMP
IMP: 通过突变表型推断
18768888 MGI
acts upstream of or within positive regulation of interleukin-13 production IMP
IMP: 通过突变表型推断
18768888 MGI
acts upstream of or within positive regulation of interleukin-5 production IMP
IMP: 通过突变表型推断
18768888 MGI
involved in protein catabolic process IDA
IDA: 通过直接分析推断
28561022 MGI
involved in response to virus IDA
IDA: 通过直接分析推断
33723527 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
17911633 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-17 receptor A

IL-17 receptor A

IL-17RA

重组 Il17ra 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72583 IL-17RA Protein, Mouse (HEK293, Fc) Q60943 (S32-W322) ≥95%
HY-P74827 IL-17RA Protein, Mouse (HEK293, His) Q60943/NP_032385.1 (S32-W322) ≥95%

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9924 Ixekizumab Inhibitor 99.00% 否
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06702 IL17RA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il17ra NCBI NCBI:23765
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