2. Gene
  3. Il2rg - interleukin 2 receptor, gamma chain Gene

Il2rg - interleukin 2 receptor, gamma chain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: gc; p64; [g]c; CD132; gamma(c)

基因 ID: 16186 | 基因类型: protein coding

关于 Il2rg

功能概要

This gene encodes a transmembrane protein that is a common subunit of several interleukin receptor complexes. These receptors are comprised of alpha and beta subunits in addition to this gamma subunit. Signalling through this pathway in important in immune cell differentiation and function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Il2rg 基因产物(2)

mRNA Protein Name
NM_001308535.1 NP_001295464.1 cytokine receptor common subunit gamma isoform b precursor
NM_013563.4 NP_038591.1 cytokine receptor common subunit gamma isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-2 binding IPI
IPI: 通过物理相互作用推断
8262055 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of B cell differentiation IMP
IMP: 通过突变表型推断
9252128 MGI
acts upstream of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
IMP: 通过突变表型推断
16227984 MGI
acts upstream of T cell differentiation in thymus IMP
IMP: 通过突变表型推断
9252128 MGI
acts upstream of gene expression IMP
IMP: 通过突变表型推断
18958875 MGI
acts upstream of lymphocyte differentiation IMP
IMP: 通过突变表型推断
23918385 MGI
acts upstream of mature B cell differentiation IMP
IMP: 通过突变表型推断
23918385 MGI
acts upstream of or within positive regulation of B cell differentiation IMP
IMP: 通过突变表型推断
9252128 MGI
acts upstream of or within positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
IMP: 通过突变表型推断
16227984 MGI
acts upstream of or within positive regulation of T cell differentiation in thymus IMP
IMP: 通过突变表型推断
9252128 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
18958875 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
9916699 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
8262055 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytokine receptor common subunit gamma

IL-2 receptor subunit gamma

IL-2R subunit gamma

common gamma chain

gamma C receptor

interleukin-2 receptor subunit gamma

重组 Il2rg 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70693 IL-2R gamma/CD132 Protein, Mouse (HEK293, His) Q3UPA9 (S25-A263) ≥95%
HY-P74807 IL-2R gamma/CD132 Protein, Mouse (HEK293, His-Fc) P34902/NP_038591.1 (W23-A263) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06750 IL2RG Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il2rg NCBI NCBI:3561
Macaca fascicularis Il2rg NCBI NCBI:102144912
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