1. Gene
  2. Il7 - interleukin 7 Gene

Il7 - interleukin 7 Gene

种属: Mus musculus

同用名: Il-7; hlb368; A630026I06Rik

基因 ID: 16196 | 基因类型: protein coding

关于 Il7

功能概要

The protein encoded by this gene is a hematopoietic growth factor important for B and T cell development. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Il7 基因产物(4)

mRNA Protein Name
NM_001313888.1 NP_001300817.1 interleukin-7 isoform b
NM_001313889.1 NP_001300818.1 interleukin-7 isoform c
NM_001313890.1 NP_001300819.1 interleukin-7 isoform b
NM_008371.5 NP_032397.1 interleukin-7 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
12490655 MGI
enables growth factor activity IDA
IDA: 通过直接分析推断
12970760 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of B cell proliferation IGI
IGI: 通过遗传相互作用推断
7671324 MGI
acts upstream of or within T cell lineage commitment IMP
IMP: 通过突变表型推断
9252127 MGI
acts upstream of or within bone resorption IDA
IDA: 通过直接分析推断
12490655 MGI
acts upstream of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
10429671 MGI
acts upstream of or within homeostasis of number of cells within a tissue IMP
IMP: 通过突变表型推断
9252127 MGI
acts upstream of or within negative regulation of catalytic activity IDA
IDA: 通过直接分析推断
8950980 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
10429671 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
8950980 MGI
acts upstream of organ growth IGI
IGI: 通过遗传相互作用推断
9252127 MGI
acts upstream of organ growth IMP
IMP: 通过突变表型推断
9252127 MGI
acts upstream of or within positive regulation of B cell differentiation IDA
IDA: 通过直接分析推断
16797412 MGI
acts upstream of or within positive regulation of B cell proliferation IDA
IDA: 通过直接分析推断
12970760 MGI
acts upstream of or within positive regulation of B cell proliferation IGI
IGI: 通过遗传相互作用推断
7671324 MGI
acts upstream of or within positive regulation of T cell differentiation IDA
IDA: 通过直接分析推断
12431371 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
16797412 MGI
acts upstream of or within positive regulation of organ growth IGI
IGI: 通过遗传相互作用推断
9252127 MGI
acts upstream of or within positive regulation of organ growth IMP
IMP: 通过突变表型推断
9252127 MGI
acts upstream of or within regulation of gene expression IDA
IDA: 通过直接分析推断
8950980 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
9252127 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
29581031 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
8950980 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-7

重组 Il7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7082 IL-7 Protein, Mouse (CHO) P10168/Q544C8/NP_032397.1 (E26-I154) ≥95%
HY-P70566 IL-7 Protein, Mouse (HEK293, His) P10168/Q544C8/NP_032397.1 (E26-I154) ≥95%
HY-P73226 IL-7 Protein, Mouse P10168/Q544C8/NP_032397.1 (E26-I154) ≥95%
HY-P700217AF Animal-Free IL-7 Protein, Mouse (His) P10168/Q544C8/NP_032397.1 (E26-I154) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il7 NCBI NCBI:3574
Macaca fascicularis Il7 NCBI NCBI:102135001
Rattus norvegicus Il7 NCBI NCBI:25647