2. Gene
  3. Fabp5 - fatty acid binding protein 5, epidermal Gene

Fabp5 - fatty acid binding protein 5, epidermal Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Klbp; mal1; Fabpe; E-FABP; PA-FABP

基因 ID: 16592 | 基因类型: protein coding

关于 Fabp5

功能概要

The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. In humans this gene has been associated with psoriasis and type 2 diabetes. In mouse deficiency of this gene in combination with a deficiency in Fabp4 confers protection against atherosclerosis, diet-induced obesity, Insulin resistance and experimental autoimmune encephalomyelitis (the mouse model for multiple sclerosis). Alternative splicing results in multiple transcript variants that encode different protein isoforms. The mouse genome contains many pseudogenes similar to this locus. [provided by RefSeq, Jan 2013]

Fabp5 基因产物(3)

mRNA Protein Name
NM_001272097.1 NP_001259026.1 fatty acid-binding protein 5 isoform 2
NM_001272098.1 NP_001259027.1 uncharacterized protein LOC16592 isoform 3
NM_010634.3 NP_034764.1 fatty acid-binding protein 5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables retinoic acid binding IDA
IDA: 通过直接分析推断
17512406 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
12540600 MGI
acts upstream of or within glucose metabolic process IMP
IMP: 通过突变表型推断
12540600 MGI
acts upstream of or within lipid metabolic process IMP
IMP: 通过突变表型推断
12540600 MGI
acts upstream of or within negative regulation of D-glucose transmembrane transport IMP
IMP: 通过突变表型推断
12540600 MGI
acts upstream of or within phosphatidylcholine biosynthetic process IGI
IGI: 通过遗传相互作用推断
15164767 MGI
involved in positive regulation of cold-induced thermogenesis IGI
IGI: 通过遗传相互作用推断
24603714 MGI
involved in positive regulation of peroxisome proliferator activated receptor signaling pathway IMP
IMP: 通过突变表型推断
17512406 MGI
involved in regulation of prostaglandin biosynthetic process IMP
IMP: 通过突变表型推断
29440395 MGI
involved in regulation of retrograde trans-synaptic signaling by endocanabinoid IDA
IDA: 通过直接分析推断
29531087 MGI
involved in regulation of sensory perception of pain IMP
IMP: 通过突变表型推断
29440395 MGI
involved in retrograde trans-synaptic signaling by endocannabinoid EXP
EXP: 通过实验结果推断
29531087 MGI
involved in retrograde trans-synaptic signaling by endocannabinoid IDA
IDA: 通过直接分析推断
29531087 MGI
involved in retrograde trans-synaptic signaling by endocannabinoid IMP
IMP: 通过突变表型推断
29531087 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17512406 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
29531087 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
29531087 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
29531087 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
29531087 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17512406 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
29531087 MGI
is active in postsynaptic cytosol IMP
IMP: 通过突变表型推断
29531087 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
29531087 MGI
is active in postsynaptic density, intracellular component IDA
IDA: 通过直接分析推断
29531087 MGI
is active in postsynaptic density, intracellular component IMP
IMP: 通过突变表型推断
29531087 MGI
located in synapse IDA
IDA: 通过直接分析推断
29531087 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fatty acid-binding protein 5

uncharacterized protein LOC16592

epidermal-type fatty acid-binding protein

epithelial fatty acid-binding protein

fatty acid-binding protein, epidermal

keratinocyte lipid-binding protein

psoriasis-associated fatty acid-binding protein homolog

重组 Fabp5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79398 FABP5 Protein, Mouse (His) Q05816 (M1-Q135) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101903 BMS-309403 Inhibitor 99.93% 否
HY-101903A BMS-309403 sodium Inhibitor 99.94% 否
HY-145990 FABPs ligand 6 Inhibitor 98.57% 否
HY-159115 ART26.12 Inhibitor 99.57% 否
HY-161702 RO6806051 Inhibitor 99.84% 否
HY-N8144 Niga-ichigoside F1 ≥99.0% 否
HY-RS04661 FABP5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160456 FABP4/5-IN-4 Inhibitor / 否
HY-160457 FABP4/5-IN-5 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fabp5 NCBI NCBI:2171
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