2. Gene
  3. Fgf23 - fibroblast growth factor 23 Gene

Fgf23 - fibroblast growth factor 23 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Fgf8b

基因 ID: 170583 | 基因类型: protein coding

关于 Fgf23

功能概要

Predicted to enable growth factor activity and type 1 Fibroblast Growth Factor receptor binding activity. Involved in several processes, including cellular response to hormone stimulus; cellular response to interleukin-6; and cellular response to vitamin D. Located in extracellular space. Biomarker of chronic kidney disease and uremia. Human ortholog(s) of this gene implicated in autosomal dominant hypophosphatemic rickets. Orthologous to human FGF23 (Fibroblast Growth Factor 23). [provided by Alliance of Genome Resources, Apr 2022]

Fgf23 基因产物(1)

mRNA Protein Name
NM_130754.2 NP_570110.1 fibroblast growth factor 23 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
23263654 RGD
involved in cellular response to leptin stimulus IEP
IEP: 通过表达模式推断
23263654 RGD
involved in cellular response to parathyroid hormone stimulus IEP
IEP: 通过表达模式推断
20685823 RGD
involved in cellular response to vitamin D IEP
IEP: 通过表达模式推断
23263654 RGD
involved in negative regulation of hormone secretion IDA
IDA: 通过直接分析推断
17992255 RGD
involved in response to magnesium ion IEP
IEP: 通过表达模式推断
23608165 RGD
involved in response to sodium phosphate IEP
IEP: 通过表达模式推断
24625659 RGD
involved in vitamin D metabolic process IEP
IEP: 通过表达模式推断
15531762 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15531762 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor 23

FGF-23

fibroblast growth factor 8b

重组 Fgf23 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72195 FGF-23 Protein, Rat (His) Q8VI82 (Y25-V251) ≥95%
HY-P700493 FGF-23 Protein, Rat (P. pastoris, His) Q8VI82 (Y25-V251) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-N1428C Ferric citrate Activator ≥98.0% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125961 T3Inh-1 Inhibitor 98.82% 否
HY-150687 ZINC12409120 Inhibitor / 否
HY-RS04900 FGF23 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgf23 NCBI NCBI:8074
Mus musculus Fgf23 NCBI NCBI:64654
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