1. Gene
  2. Trak2 - trafficking kinesin protein 2 Gene

Trak2 - trafficking kinesin protein 2 Gene

种属: Rattus norvegicus

同用名: GRIF-1; Als2cr3

基因 ID: 171086 | 基因类型: protein coding

关于 Trak2

功能概要

Enables several functions, including GABA Receptor binding activity; TPR domain binding activity; and Kinesin binding activity. Involved in several processes, including dendritic transport of mitochondrion; endosome to lysosome transport; and generation of neurons. Located in several cellular components, including axonal growth cone; dendrite; and neuronal cell body. Colocalizes with early endosome. Orthologous to human TRAK2 (trafficking Kinesin protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Trak2 基因产物(1)

mRNA Protein Name
NM_133560.2 NP_598244.2 trafficking kinesin-binding protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GABA receptor binding IDA
IDA: 通过直接分析推断
12034717 RGD
enables GABA receptor binding IMP
IMP: 通过突变表型推断
12034717 RGD
enables TPR domain binding IDA
IDA: 通过直接分析推断
12435728 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
12435728 RGD
enables kinesin binding IDA
IDA: 通过直接分析推断
15644324 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12435728 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
12034717 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
23395375 RGD
involved in dendritic transport of mitochondrion IMP
IMP: 通过突变表型推断
23395375 RGD
involved in endosome to lysosome transport IDA
IDA: 通过直接分析推断
17062640 RGD
involved in negative regulation of axonogenesis IMP
IMP: 通过突变表型推断
23395375 RGD
involved in protein O-linked glycosylation IDA
IDA: 通过直接分析推断
12435728 RGD
involved in protein targeting IDA
IDA: 通过直接分析推断
12435728 RGD
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12435728 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axonal growth cone IDA
IDA: 通过直接分析推断
25653102 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
12034717 RGD
located in dendrite IDA
IDA: 通过直接分析推断
25653102 RGD
located in early endosome IDA
IDA: 通过直接分析推断
17062640 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
19528298 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
25653102 RGD
located in nucleus IDA
IDA: 通过直接分析推断
12034717 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
12034717 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

trafficking kinesin-binding protein 2

GABA-A receptor interacting factor-1

O-GlcNAc transferase-interacting protein of 98 kDa

amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 homolog

amyotrop

Trak2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Trak2 Q8R2H7 KIF5A Homo sapiens Q12840
Anti Tag CoIP
24161670
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trak2 NCBI NCBI:66008