2. Gene
  3. DPYSL3 - dihydropyrimidinase like 3 Gene

DPYSL3 - dihydropyrimidinase like 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：二氢嘧啶酶 3

种属: Homo sapiens

同用名: DRP3; ULIP; CRMP4; DRP-3; LCRMP; CRMP-4; ULIP-1

基因 ID: 1809 | 基因类型: protein coding

关于 DPYSL3

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:147,390,808-147,510,068 (from NCBI)

This gene has 9 transcripts (splice variants), 212 orthologues and 5 paralogues. Broad expression in brain (RPKM 51.8), prostate (RPKM 49.3) and 22 other tissues.

功能概要

启用细丝蛋白结合活性。预计参与多个过程，包括肌动蛋白丝组织；质膜结合细胞投射组织的调节；和对轴突损伤的反应。预计在神经系统发育的上游或内部起作用。预测位于多个细胞成分中，包括细胞体；生长锥;和片状足。预测是丝状肌动蛋白的一部分。预测在突触中活跃。预测与胞吐囊泡共定位。 [由基因组资源联盟提供，2022 年 4 月]

Enables filamin binding activity. Predicted to be involved in several processes, including actin filament organization; regulation of plasma membrane bounded cell projection organization; and response to axon injury. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including cell body; growth cone; and lamellipodium. Predicted to be part of filamentous actin. Predicted to be active in synapse. Predicted to colocalize with exocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

DPYSL3 基因产物(2)

mRNA Protein Name
NM_001197294.2 NP_001184223.1 dihydropyrimidinase-related protein 3 isoform 1
NM_001387.3 NP_001378.1 dihydropyrimidinase-related protein 3 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables filamin binding IPI
IPI: 通过物理相互作用推断
25358863 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
21044950 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DPYSL3 蛋白结构

Amidohydro_1

Amidohydro_1: Amidohydrolase family (64 - 413)

  • 0
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  • 500
  • 570 a.a.
蛋白主名 其他名称

dihydropyrimidinase-related protein 3

collapsin response mediator protein 4 long

重组 DPYSL3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71546 DPYSL3 Protein, Human (His) Q14195 (1M-570S) ≥95%

关联疾病

疾病名称 别名
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03982 DPYSL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus DPYSL3 VGNC VGNC:28196
Rattus norvegicus DPYSL3 RGD RGD:2410
Canis familiaris DPYSL3 VGNC VGNC:40084
Felis catus DPYSL3 VGNC VGNC:61616
Macaca mulatta DPYSL3 VGNC VGNC:71985
Mus musculus DPYSL3 MGD MGI:1349762
Others DPYSL3 NCBI
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