1. Gene
  2. P2ry1 - purinergic receptor P2Y, G-protein coupled 1 Gene

P2ry1 - purinergic receptor P2Y, G-protein coupled 1 Gene

中文名称:嘌呤能受体 P2 Y,G 蛋白偶联 1

种属: Mus musculus

同用名: P2Y1; P2y1r

基因 ID: 18441 | 基因类型: protein coding

关于 P2ry1

Chromosome 3: 60,910,216-60,916,403 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 191 orthologues, 13 paralogues and is associated with 4 phenotypes. Ubiquitous expression in colon adult (RPKM 5.3), large intestine adult (RPKM 4.9) and 27 other tissues.

功能概要

预计该基因编码的蛋白具有多种功能,包括 A1 腺苷受体结合活性; G 蛋白偶联嘌呤核苷酸受体活性;和腺苷酸核糖核苷酸结合活性。在细胞对有机环状化合物的反应和离子传输的正向调节的上游或内部起作用。位于质膜。以多种结构表达,包括消化系统;脑;泌尿生殖系统;外皮系统;以及肝脏和胆道系统。与人 P2RY1(嘌呤能受体 P2Y1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable several functions, including A1 Adenosine Receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Acts upstream of or within cellular response to organic cyclic compound and positive regulation of ion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and liver and biliary system. Orthologous to human P2RY1 (purinergic receptor P2Y1). [provided by Alliance of Genome Resources, Apr 2022]

P2ry1 基因产物(2)

mRNA Protein Name
NM_008772.5 NP_032798.1 P2Y purinoceptor 1
NM_001282016.1 NP_001268945.1 P2Y purinoceptor 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: 通过直接分析推断
23479225 MGI
acts upstream of establishment of localization in cell IGI
IGI: 通过遗传相互作用推断
15914557 MGI
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
15914557 MGI
acts upstream of monoatomic ion transport IGI
IGI: 通过遗传相互作用推断
15914557 MGI
acts upstream of monoatomic ion transport IMP
IMP: 通过突变表型推断
15914557 MGI
acts upstream of or within positive regulation of monoatomic ion transport IGI
IGI: 通过遗传相互作用推断
15914557 MGI
acts upstream of or within positive regulation of monoatomic ion transport IMP
IMP: 通过突变表型推断
15914557 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
15670583 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

P2ry1 蛋白结构

7tmA_P2Y1

7tmA_P2Y1: cd15377 (51 - 334)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (51 - 78)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (85 - 110)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (123 - 153)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (165 - 187)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (213 - 242)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (252 - 282)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (302 - 327)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
蛋白主名 其他名称

P2Y purinoceptor 1

ADP receptor

ATP receptor

P2Y1 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2ry1 NCBI NCBI:5028