2. Gene
  3. P2ry2 - purinergic receptor P2Y, G-protein coupled 2 Gene

P2ry2 - purinergic receptor P2Y, G-protein coupled 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：嘌呤能受体 P2 Y，G 蛋白偶联 2

种属: Mus musculus

同用名: P2U1; P2Y2

基因 ID: 18442 | 基因类型: protein coding

关于 P2ry2

Chromosome 7: 100,645,775-100,662,073 reverse strand.GRCm39:CM001000.3

This gene has 6 transcripts (splice variants), 201 orthologues, 13 paralogues and is associated with 4 phenotypes. Broad expression in heart adult (RPKM 12.3), small intestine adult (RPKM 1.9) and 18 other tissues.

功能概要

预测该基因编码的蛋白可启动A1腺苷受体结合活性； ATP结合活性；和 G 蛋白偶联的 UTP 受体活性。在粘液分泌的正调节上游或内部起作用。预测位于顶端质膜和基底外侧质膜。预计与早期内体共定位；溶酶体；和线粒体。与人 P2RY2（嘌呤能受体 P2Y2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable A1 Adenosine Receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Acts upstream of or within positive regulation of mucus secretion. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to colocalize with early endosome; lysosome; and mitochondrion. Orthologous to human P2RY2 (purinergic receptor P2Y2). [provided by Alliance of Genome Resources, Apr 2022]

P2ry2 基因产物(3)

mRNA Protein Name
NM_008773.4 NP_032799.2 P2Y purinoceptor 2
NM_001302346.1 NP_001289275.1 P2Y purinoceptor 2
NM_001302347.1 NP_001289276.1 P2Y purinoceptor 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
17728398 MGI
acts upstream of mucus secretion IMP
IMP: 通过突变表型推断
17728398 MGI
acts upstream of or within positive regulation of mucus secretion IMP
IMP: 通过突变表型推断
17728398 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

P2ry2 蛋白结构

7tmA_P2Y2

7tmA_P2Y2: cd15373 (33 - 60)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (33 - 316)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (67 - 92)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (105 - 135)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (147 - 169)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (194 - 223)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (237 - 267)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (284 - 309)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
蛋白主名 其他名称

P2Y purinoceptor 2

ATP receptor

P2U purinoceptor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09928 P2RY2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09929 P2ry2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09930 P2ry2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2ry2 NCBI NCBI:5029
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