2. Gene
  3. P4hb - prolyl 4-hydroxylase, beta polypeptide Gene

P4hb - prolyl 4-hydroxylase, beta polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PDI; Thbp; ERp59; Pdia1

基因 ID: 18453 | 基因类型: protein coding

关于 P4hb

功能概要

Enables Integrin binding activity. Acts upstream of or within cellular response to interleukin-7. Located in endoplasmic reticulum and external side of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human P4HB (prolyl 4-hydroxylase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

P4hb 基因产物(1)

mRNA Protein Name
NM_011032.3 NP_035162.1 protein disulfide-isomerase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IPI
IPI: 通过物理相互作用推断
21670307 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21670307 MGI
enables protein-disulfide reductase activity IMP
IMP: 通过突变表型推断
31184304 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to interleukin-7 IDA
IDA: 通过直接分析推断
29581031 MGI
acts upstream of positive effect endoplasmic reticulum to Golgi vesicle-mediated transport IMP
IMP: 通过突变表型推断
31184304 MGI
involved in insulin processing IMP
IMP: 通过突变表型推断
31184304 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
9493907 MGI
part of endoplasmic reticulum chaperone complex IDA
IDA: 通过直接分析推断
12475965 MGI
is active in endoplasmic reticulum lumen IMP
IMP: 通过突变表型推断
31184304 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
21670307 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein disulfide-isomerase

ER protein 59

cellular thyroid hormone-binding protein

endoplasmic reticulum resident protein 59

p55

prolyl 4-hydroxylase subunit beta

重组 P4hb 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74658 P4HB Protein, Mouse (HEK293, His) P09103 (D20-L509) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09945 P4HB Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P4hb NCBI NCBI:5034
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