Prkaca - protein kinase, cAMP dependent, catalytic, alpha Gene

中文名称：蛋白激酶，cAMP 依赖性，催化性， α

种属: Mus musculus

同用名: PKCD; Pkaca

关于 Prkaca

功能概要

该基因编码丝氨酸/苏氨酸蛋白激酶家族的成员。全酶蛋白激酶 A（也称为环 AMP 依赖性蛋白激酶）介导细胞对环 AMP 水平变化的反应。该基因编码蛋白激酶 A 的 α 催化亚基。蛋白激酶 A 介导的信号通过靶蛋白的磷酸化转导，对许多细胞功能很重要，包括哺乳动物精子成熟和运动。可变剪接导致多个转录本变体。该基因的假基因已在 X 染色体上定义。 [RefSeq 提供，2013 年 4 月]

This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]