Prkcg - protein kinase C, gamma Gene

中文名称：蛋白激酶 C， γ

种属: Mus musculus

同用名: Pkcc; Prkcc; PKCgamma

关于 Prkcg

功能概要

预测该基因编码的蛋白可实现钙依赖性蛋白激酶 C 活性和蛋白丝氨酸/苏氨酸/酪氨酸激酶活性。涉及多个过程，包括化学突触传递的调节；细胞蛋白质代谢过程的负调节；和对吗啡的反应。在化学感应行为和吞噬作用调节的上游或内部起作用。位于几种细胞成分中，包括 Held 的花萼；突触后密度；和突触膜。在突触前细胞质中活跃。以多种结构表达，包括消化系统；中枢神经系统;早期胚胎；泌尿生殖系统；和淋巴系统腺体。该基因的人类直系同源基因与 14 型脊髓小脑性共济失调有关。与人类 PRKCG（蛋白激酶 C 伽玛）直系同源基因。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium-dependent protein kinase C activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of cellular protein metabolic process; and response to morphine. Acts upstream of or within chemosensory behavior and regulation of phagocytosis. Located in several cellular components, including calyx of Held; postsynaptic density; and synaptic membrane. Is active in presynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 14. Orthologous to human PRKCG (protein kinase C gamma). [provided by Alliance of Genome Resources, Apr 2022]