1. Gene
  2. Plxna2 - plexin A2 Gene

Plxna2 - plexin A2 Gene

种属: Mus musculus

同用名: OCT; Plxn2; PlexA2; mKIAA0463; 2810428A13Rik

基因 ID: 18845 | 基因类型: protein coding

关于 Plxna2

功能概要

Enables identical protein binding activity and semaphorin receptor activity. Involved in regulation of cell migration and semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including cerebellar granule cell precursor tangential migration; chordate embryonic development; and limb bud formation. Is integral component of plasma membrane. Is expressed in several structures, including genitourinary system; heart; lung; nervous system; and sensory organ. Orthologous to human PLXNA2 (plexin A2). [provided by Alliance of Genome Resources, Apr 2022]

Plxna2 基因产物(1)

mRNA Protein Name
NM_008882.2 NP_032908.2 plexin-A2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20877282 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20877282 MGI
enables semaphorin receptor activity IGI
IGI: 通过遗传相互作用推断
18327254 MGI
enables semaphorin receptor activity IMP
IMP: 通过突变表型推断
20877282 MGI
enables semaphorin receptor activity IPI
IPI: 通过物理相互作用推断
18327254 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
18327254 MGI
acts upstream of or within centrosome localization IMP
IMP: 通过突变表型推断
18327254 MGI
acts upstream of or within cerebellar granule cell precursor tangential migration IMP
IMP: 通过突变表型推断
18327254 MGI
involved in limb bud formation IEP
IEP: 通过表达模式推断
19666519 MGI
involved in neural tube development IEP
IEP: 通过表达模式推断
19666519 MGI
involved in pharyngeal system development IEP
IEP: 通过表达模式推断
19666519 MGI
involved in regulation of cell migration IMP
IMP: 通过突变表型推断
20877282 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
20877282 MGI
involved in somitogenesis IEP
IEP: 通过表达模式推断
19666519 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
20881961 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

plexin-A2

plex 2

plexin-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plxna2 NCBI NCBI:5362