2. Gene
  3. APOBEC3F - apolipoprotein B mRNA editing enzyme catalytic subunit 3F Gene

APOBEC3F - apolipoprotein B mRNA editing enzyme catalytic subunit 3F Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：载脂蛋白 B mRNA 编辑酶催化亚基 3F

种属: Homo sapiens

同用名: A3F; KA6; ARP8; BK150C2.4.MRNA

基因 ID: 200316 | 基因类型: protein coding

关于 APOBEC3F

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:39,040,864-39,055,972 (from NCBI)

This gene has 4 transcripts (splice variants), 52 orthologues and 9 paralogues. Broad expression in lymph node (RPKM 2.8), ovary (RPKM 2.8) and 24 other tissues.

功能概要

该基因是胞苷脱氨酶基因家族的成员。它是在一个簇中发现的七个相关基因或假基因之一，被认为是由 22 号染色体上的基因复制引起的。该簇的成员编码的蛋白质在结构和功能上与 C 到 U RNA 编辑胞苷脱氨酶 APOBEC1 相关。人们认为这些蛋白质可能是 RNA 编辑酶，在生长或细胞周期控制中发挥作用。已经鉴定出编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing Enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

APOBEC3F 基因产物(2)

mRNA Protein Name
NM_001006666.2 NP_001006667.1 DNA dC->dU-editing enzyme APOBEC-3F isoform b
NM_145298.6 NP_660341.2 DNA dC->dU-editing enzyme APOBEC-3F isoform a

APOBEC3F 蛋白结构

APOBEC_N

APOBEC_N: APOBEC-like N-terminal domain (23 - 183)

APOBEC_N

APOBEC_N: APOBEC-like N-terminal domain (200 - 371)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
蛋白主名 其他名称

DNA dC->dU-editing enzyme APOBEC-3F

apolipoprotein B editing enzyme catalytic polypeptide-like 3F

关联疾病

疾病名称 别名
Immune Deficiency Disease

Immunodeficiency

Primary Immunodeficiency

Primary Immunodeficiency Disease

Immunologic Deficiency Syndromes

Hypoimmunity

Immune Deficiency Disorder

Immunodeficiency Syndrome

Immune Disorder

Primary Immune Deficiency Disorder

Immune System Diseases

Human Immunodeficiency Virus Infection

Hiv - [Human Immunodeficiency Virus Infection]

Hiv Positive Nos

Hiv Disease

Acquired Immune Deficiency Syndrome-Related Complex

Aids-Like Syndrome

Aids-Related Complex Nos

Arc - [Aids-Related Complex]

Immunodeficiency Due To Human Immunodeficiency Virus Infection

Unspecified Human Immunodeficiency Virus Disease

Hiv Disease Nos

Human Immunodeficiency Virus Positive Nos

Hiv Nos

Deficiency Of Complement Initial Pathway

Deficiency Of Complement Terminal Pathway

Cfdd - [Complement Factor D Deficiency]

Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

Nonfamilial Hypogammaglobulinaemia

Common Variable Immune Deficiency

Nonfamilial Agammaglobulinaemia

Common Variable Agammaglobulinaemia

Agammaglobulinaemia Nos

Agammaglobulinaemia Antibody Deficiency Syndrome

Hypogammaglobulinaemia Antibody Deficiency Syndrome

Acquired Agammaglobulinaemia Nos

Hypogammaglobulinaemia Nos

Hyper Igm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00839 APOBEC3F Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-120157 Vif-ElonginC interaction inhibitor 1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus APOBEC3F MGD MGI:1933111
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