1. Gene
  2. Sell - selectin, lymphocyte Gene

Sell - selectin, lymphocyte Gene

种属: Mus musculus

同用名: Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; L-selectin

基因 ID: 20343 | 基因类型: protein coding

关于 Sell

功能概要

Enables cell adhesion molecule binding activity. Acts upstream of or within response to ATP. Located in external side of plasma membrane. Is expressed in brain; brainstem; submandibular gland epithelium; and testis. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in Crohn's disease; IgA glomerulonephritis; and ulcerative colitis. Orthologous to human SELL (Selectin L). [provided by Alliance of Genome Resources, Apr 2022]

Sell 基因产物(4)

mRNA Protein Name
NM_001164059.1 NP_001157531.1 L-selectin isoform 2 precursor
NM_011346.2 NP_035476.1 L-selectin isoform 1 precursor
NM_001164059.1 NP_001157531.1 L-selectin isoform 2 precursor
NM_011346.2 NP_035476.1 L-selectin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IPI
IPI: 通过物理相互作用推断
14597732 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11389866 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within response to ATP IDA
IDA: 通过直接分析推断
15914561 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
23620790 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
7589135 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11389866 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

L-selectin

CD62 antigen-like family member L

LAM-1

LECAM1

leukocyte adhesion molecule 1

leukocyte-endothelial cell adhesion molecule 1

lymph node homing receptor

lymphocyte antigen 22

lymphocyte surface MEL-14 antigen

重组 Sell 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70312 L-selectin/CD62L Protein, Mouse (294a.a, HEK293, C-Fc-His) P18337 (W39-N332) ≥95%
HY-P74766 L-selectin/CD62L Protein, Mouse (3332a.a, HEK293, His) NP_035476.1 (W39-N332) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sell NCBI NCBI:6402
Macaca fascicularis Sell NCBI NCBI:102142895
Rattus norvegicus Sell NCBI NCBI:29259