1. Gene
  2. Sell - selectin L Gene

Sell - selectin L Gene

种属: Rattus norvegicus

同用名: A.11; LECAM-1; L-selectin

基因 ID: 29259 | 基因类型: protein coding

关于 Sell

功能概要

Enables glycolipid binding activity. Involved in several processes, including positive regulation of neutrophil chemotaxis; response to fatty acid; and response to hyperoxia. Located in cell surface. Used to study colitis and peripheral vascular disease. Biomarker of abdominal aortic aneurysm; endometriosis; pancreatitis; and toxic shock syndrome. Human ortholog(s) of this gene implicated in Crohn's disease; IgA glomerulonephritis; and ulcerative colitis. Orthologous to human SELL (Selectin L). [provided by Alliance of Genome Resources, Apr 2022]

Sell 基因产物(1)

mRNA Protein Name
NM_019177.4 NP_062050.3 L-selectin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycolipid binding IDA
IDA: 通过直接分析推断
7678958 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of neutrophil chemotaxis IMP
IMP: 通过突变表型推断
15677732 RGD
involved in regulation of apoptotic process IDA
IDA: 通过直接分析推断
18054560 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
12730074 RGD
involved in response to linoleic acid IEP
IEP: 通过表达模式推断
20730605 RGD
involved in response to oleic acid IEP
IEP: 通过表达模式推断
20730605 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
17177850 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

L-selectin

CD62 antigen-like family member L

LAM-1

LECAM1

leukocyte adhesion molecule 1

leukocyte-endothelial cell adhesion molecule 1

ly-22

lymph node homing receptor

lymphocyte antigen 22

lymphocyte surface MEL-14 antigen

selectin, lymphocyte

重组 Sell 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76638 L-Selectin/CD62L Protein, Rat (HEK293, His) P30836 (W39-N332) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sell NCBI NCBI:6402
Macaca fascicularis Sell NCBI NCBI:102142895
Mus musculus Sell NCBI NCBI:20343