2. Gene
  3. NR2F6 - nuclear receptor subfamily 2 group F member 6 Gene

NR2F6 - nuclear receptor subfamily 2 group F member 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核受体亚家族 2 F 组成员 6

种属: Homo sapiens

同用名: EAR2; EAR-2; ERBAL2

基因 ID: 2063 | 基因类型: protein coding

关于 NR2F6

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,231,883-17,245,919 (from NCBI)

This gene has 2 transcripts (splice variants), 285 orthologues and 11 paralogues. Broad expression in colon (RPKM 27.8), stomach (RPKM 20.8) and 23 other tissues.

功能概要

启用 DNA 结合转录因子活性和序列特异性双链 DNA 结合活性。参与 RNA 聚合酶 II 对转录的负调控。位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NR2F6 基因产物(1)

mRNA Protein Name
NM_005234.4 NP_005225.2 nuclear receptor subfamily 2 group F member 6

NR2F6 蛋白结构

zf-C4

zf-C4: Zinc finger, C4 type (two domains) (55 - 123)

Hormone_recep

Hormone_recep: Ligand-binding domain of nuclear hormone receptor (198 - 376)

  • 0
  • 100
  • 200
  • 300
  • 404 a.a.
蛋白主名 其他名称

nuclear receptor subfamily 2 group F member 6

ERBA-related gene-2

NR2F6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
NR2F6 P10588 NR2F2 Homo sapiens P24468
Anti Tag CoIP
33961781
种属内
NR2F6 P10588 NAP1L1 Homo sapiens P55209
Display Tech
20195357
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Sebaceous Adenocarcinoma

Sebaceous Carcinoma

Adenocarcinoma Of The Sebaceous Gland

Malignant Neoplasm Of Sebaceous Gland

Malignant Sebaceous Tumor

Adenocarcinoma, Sebaceous

Malignant Sebaceous Neoplasm

Sebaceous Gland Neoplasms
46,Xy Sex Reversal

Swyer Syndrome

Pure Gonadal Dysgenesis 46,Xy

Gonadal Dysgenesis, Xy Female Type

Gonadal Dysgenesis, 46,Xy

46,Xy Cgd

46,Xy Complete Gonadal Dysgenesis

46,Xy Pure Gonadal Dysgenesis

46 Xy Gonadal Dysgenesis

46, Xy Cgd

46, Xy Complete Gonadal Dysgenesis

46, Xy Pure Gonadal Dysgenesis

Xy Pure Gonadal Dysgenesis

Female With 46,Xy Karyotype

Xy Females
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-147228 NR2F6 modulator-1 99.74% 否
HY-156190 NR2F2-IN-1 / 否
HY-118912 BMH-9 Modulator / 否
HY-RS09543 NR2F6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus NR2F6 MGD MGI:1352453
Felis catus NR2F6 VGNC VGNC:68552
Macaca mulatta NR2F6 VGNC VGNC:75514
Rattus norvegicus NR2F6 RGD RGD:621685
Canis familiaris NR2F6 VGNC VGNC:43951
Bos taurus NR2F6 VGNC VGNC:32242
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