1. Gene
  2. Btla - B and T lymphocyte associated Gene

Btla - B and T lymphocyte associated Gene

种属: Mus musculus

同用名: A630002H24

基因 ID: 208154 | 基因类型: protein coding

关于 Btla

功能概要

Enables signaling receptor activity. Acts upstream of or within immune response-regulating cell surface receptor signaling pathway; negative regulation of B cell proliferation; and negative regulation of alpha-beta T cell proliferation. Located in external side of plasma membrane. Is integral component of plasma membrane. Orthologous to human BTLA (B and T lymphocyte associated). [provided by Alliance of Genome Resources, Apr 2022]

Btla 基因产物(2)

mRNA Protein Name
NM_001037719.2 NP_001032808.2 B- and T-lymphocyte attenuator isoform 1 precursor
NM_177584.3 NP_808252.1 B- and T-lymphocyte attenuator isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12796776 MGI
enables signaling receptor activity IGI
IGI: 通过遗传相互作用推断
12920180 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
15568026 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12796776 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

B- and T-lymphocyte attenuator

B- and T-lymphocyte-associated protein

重组 Btla 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75467 BTLA/CD272 Protein, Mouse (HEK293, hFc) Q32MV9 (E30-G176) ≥95%
HY-P78246 BTLA/CD272 Protein, Mouse (HEK293, His) Q32MV9 (E30-G176) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Btla NCBI NCBI:151888
Macaca fascicularis Btla NCBI NCBI:102144877
Rattus norvegicus Btla NCBI NCBI:407756
Macaca mulatta Btla NCBI NCBI:708202