2. Gene
  3. Thpo - thrombopoietin Gene

Thpo - thrombopoietin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ml; Tpo; Mgdf; Mpllg

基因 ID: 21832 | 基因类型: protein coding

关于 Thpo

功能概要

This gene encodes a humoral growth factor necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. The encoded protein is a ligand for the product of the myeloproliferative leukemia virus oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Thpo 基因产物(4)

mRNA Protein Name
NM_001173505.1 NP_001166976.1 thrombopoietin isoform 1 precursor
NM_001289894.1 NP_001276823.1 thrombopoietin isoform 2 precursor
NM_001289896.1 NP_001276825.1 thrombopoietin isoform 3 precursor
NM_009379.3 NP_033405.1 thrombopoietin isoform 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within myeloid cell differentiation IDA
IDA: 通过直接分析推断
12393382 MGI
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
22128142 MGI
involved in positive regulation of megakaryocyte differentiation IDA
IDA: 通过直接分析推断
22128142 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
22128142 MGI
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
22128142 MGI
involved in thrombopoietin-mediated signaling pathway IDA
IDA: 通过直接分析推断
22128142 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thrombopoietin

C-mpl ligand

megakaryocyte colony-stimulating factor

megakaryocyte growth and development factor

myeloproliferative leukemia virus oncogene ligand

重组 Thpo 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7088 TPO/Thrombopoietin Protein, Mouse (CHO) P40226-1 (S22-T356) ≥95%
HY-P70686 TPO/Thrombopoietin Protein, Mouse (335a.a, HEK293, His) P40226-1 (S22-T356) ≥95%
HY-P70686A TPO/Thrombopoietin Protein, Mouse (335a.a, HEK293, C-His) P40226-1 (S22-T356) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14498 THPO Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Thpo NCBI NCBI:7066
Macaca fascicularis Thpo NCBI NCBI:102144240
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