1. Gene
  2. SLC16A9 - solute carrier family 16 member 9 Gene

SLC16A9 - solute carrier family 16 member 9 Gene

中文名称:溶质载体家族 16 成员 9

种属: Homo sapiens

同用名: MCT9; C10orf36

基因 ID: 220963 | 基因类型: protein coding

关于 SLC16A9

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:59,650,764-59,710,079 (from NCBI)

This gene has 3 transcripts (splice variants), 275 orthologues and 13 paralogues. Biased expression in adrenal (RPKM 82.1), kidney (RPKM 62.2) and 9 other tissues.

功能概要

预计可启用单羧酸跨膜转运蛋白活性。参与尿酸盐代谢过程。预计是质膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable monocarboxylic acid transmembrane transporter activity. Involved in urate metabolic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A9 基因产物(6)

mRNA Protein Name
NM_001323977.1 NP_001310906.1 monocarboxylate transporter 9 isoform b
NM_001323978.2 NP_001310907.1 monocarboxylate transporter 9 isoform b
NM_001323979.2 NP_001310908.1 monocarboxylate transporter 9 isoform b
NM_001323980.2 NP_001310909.1 monocarboxylate transporter 9 isoform b
NM_001323981.2 NP_001310910.1 monocarboxylate transporter 9 isoform a
NM_194298.3 NP_919274.1 monocarboxylate transporter 9 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carnitine transmembrane transporter activity IDA
IDA: 通过直接分析推断
21886157 GOA
enables creatine transmembrane transporter activity IDA
IDA: 通过直接分析推断
31784090 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in carnitine transmembrane transport IDA
IDA: 通过直接分析推断
21886157 GOA
involved in creatine transmembrane transport IDA
IDA: 通过直接分析推断
31784090 GOA
involved in urate metabolic process IMP
IMP: 通过突变表型推断
19503597 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
31784090 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SLC16A9 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (21 - 422)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 509 a.a.
蛋白主名 其他名称

monocarboxylate transporter 9

MCT 9

SLC16A9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC16A9 Q7RTY1 MRPL11 Homo sapiens Q9Y3B7
Y2H Array
25416956
Intra SLC16A9 Q7RTY1 MRPL11 Homo sapiens Q9Y3B7
Y2H Prey Pooling
25416956
Intra SLC16A9 Q7RTY1 EIF4A2 Homo sapiens Q14240
Y2H Array
25416956
Intra SLC16A9 Q7RTY1 KLC4 Homo sapiens Q9NSK0
Validated Y2H
25416956
Intra SLC16A9 Q7RTY1 KLC4 Homo sapiens Q9NSK0
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Gout

Gouty Arthritis

Articular Gout

Gouty Arthropathy

Arthritis, Gouty

Arthritis Gouty

Idiopathic Gout

Idiopathic Gout, Unspecified Site

Gouty Bursitis

Uratic Arthritis

Gout Nos

Gouty

Gouty Diathesis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SLC16A9 VGNC VGNC:77564
Canis familiaris SLC16A9 VGNC VGNC:46247
Bos taurus SLC16A9 VGNC VGNC:34695
Mus musculus SLC16A9 MGD MGI:1914109
Felis catus SLC16A9 VGNC VGNC:65216
Rattus norvegicus SLC16A9 RGD RGD:1596295