FGD2 - FYVE, RhoGEF and PH domain containing 2 Gene

中文名称：含 FYVE、RhoGEF 和 PH 域 2

种属: Homo sapiens

同用名: ZFYVE4

关于 FGD2

功能概要

该基因编码的蛋白质属于鸟嘌呤核苷酸交换因子 (GEF) 家族，它通过激活细胞分裂周期 42 (CDC42) 蛋白质来控制细胞骨架依赖性膜重排。该基因在 B 淋巴细胞、巨噬细胞和树突状细胞中表达。编码的蛋白质可能在免疫系统中抗原呈递细胞的白细胞信号传导和囊泡运输中发挥作用。[RefSeq 提供，2016 年 10 月]

The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016]