PLEKHG4 - pleckstrin homology and RhoGEF domain containing G4 Gene

种属: Homo sapiens (human)

同用名: SCA4; PRTPHN1; ARHGEF44

基因 ID: 25894 | 基因类型: protein coding

关于 PLEKHG4

功能概要

The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and Cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

PLEKHG4 基因产物(1)

mRNA	Protein	Name
NM_001129728.2	NP_001123200.1	puratrophin-1 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

puratrophin-1

PH domain-containing family G member 4	Purkinje cell atrophy associated protein 1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4

PLEKHG4 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	PLEKHG4	Q58EX7	MYEF2	Homo sapiens	Q9P2K5-2	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	FGD2	Homo sapiens	Q7Z6J4	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	MSRB3	Homo sapiens	Q8IXL7-2	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	PKP2	Homo sapiens	Q99959-2	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	ZNF148	Homo sapiens	Q9UQR1-2	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TFAP2D	Homo sapiens	Q7Z6R9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	ZNF648	Homo sapiens	Q5T619	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	ZNF319	Homo sapiens	Q9P2F9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SAXO4	Homo sapiens	Q7Z5V6-2	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SHISA6	Homo sapiens	Q6ZSJ9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	DPPA3	Homo sapiens	Q6W0C5	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SETD5	Homo sapiens	Q9C0A6-3	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	MGC50722	Homo sapiens	Q8IVT4	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	PRPF31	Homo sapiens	Q8WWY3	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	MALSU1	Homo sapiens	Q96EH3	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	PRPF18	Homo sapiens	Q99633	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	A1CF	Homo sapiens	Q9NQ94	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SMG9	Homo sapiens	Q9H0W8	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TFG	Homo sapiens	Q92734	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	PSMB1	Homo sapiens	P20618	Y2H Array	32296183
种属内	PLEKHG4	Q58EX7	TSSK3	Homo sapiens	Q96PN8	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	ZCCHC14	Homo sapiens	Q8WYQ9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SAXO1	Homo sapiens	Q8IYX7	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	FAM161A	Homo sapiens	Q3B820	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	MDFI	Homo sapiens	Q99750	Y2H Prey Pooling	25416956
种属内	PLEKHG4	Q58EX7	MDFI	Homo sapiens	Q99750	Validated Y2H	25416956
种属内	PLEKHG4	Q58EX7	DTX2	Homo sapiens	Q86UW9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	CHIC2	Homo sapiens	Q9UKJ5	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	ARMC7	Homo sapiens	Q9H6L4	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	MYOZ1	Homo sapiens	Q9NP98	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	CCDC120	Homo sapiens	Q96HB5	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TENT5D	Homo sapiens	Q8NEK8	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	BEX2	Homo sapiens	Q9BXY8	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	SH2D4A	Homo sapiens	Q9H788	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	DUSP13B	Homo sapiens	Q9UII6	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TEKT3	Homo sapiens	Q9BXF9	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	NATD1	Homo sapiens	Q8N6N6	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TBC1D22B	Homo sapiens	Q9NU19	Validated Y2H	32296183
种属内	PLEKHG4	Q58EX7	TTC23	Homo sapiens	Q5W5X9-3	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

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PLEKHG4 - pleckstrin homology and RhoGEF domain containing G4 Gene

关于 PLEKHG4

功能概要

PLEKHG4 基因产物(1)

PLEKHG4 蛋白互作信息

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