2. Gene
  3. PI16 - peptidase inhibitor 16 Gene

PI16 - peptidase inhibitor 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肽酶抑制因子 16

种属: Homo sapiens

同用名: CD364; PSPBP; CRISP9; MSMBBP

基因 ID: 221476 | 基因类型: protein coding

关于 PI16

This gene has 4 transcripts (splice variants) and 85 orthologues. Biased expression in urinary bladder (RPKM 35.7), heart (RPKM 28.3) and 12 other tissues.

功能概要

预测启用肽酶抑制剂活性。预计参与肽酶活性的负调节。预计在参与心肌细胞发育的细胞生长的负调节上游或负调节中起作用。预计在细胞外空间活跃。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable peptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to act upstream of or within negative regulation of cell growth involved in cardiac muscle cell development. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

PI16 基因产物(2)

mRNA Protein Name
NM_001199159.2 NP_001186088.1 peptidase inhibitor 16 precursor
NM_153370.3 NP_699201.2 peptidase inhibitor 16 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PI16 蛋白结构

CAP

CAP: Cysteine-rich secretory protein family (38 - 165)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 463 a.a.
蛋白主名 其他名称

peptidase inhibitor 16

PSP94-binding protein

PI16 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PI16 Q6UXB8 TMEM86A Homo sapiens Q8N2M4
Validated Y2H
32296183
Intra PI16 Q6UXB8 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Corneal Dystrophy, Meesmann, 1

Meesmann Corneal Dystrophy

Mecd

Corneal Dystrophy, Meesmann Epithelial

Juvenile Hereditary Epithelial Dystrophy

Corneal Dystrophy, Juvenile Epithelial Of Meesmann

MECD1

Meesmann Corneal Dystrophy 1

Meesmann Corneal Epithelial Dystrophy

Meesmann Epithelial Corneal Dystrophy

Corneal Dystrophy, Juvenile Epithelial, Of Meesmann

Stocker-Holt Dystrophy

Meesman Dystrophy

Meesman'S Corneal Dystrophy

Juvenile Hereditary Epithelial Dystrophy Of Meesmann

Corneal Dystrophy, Meesmann 1

Juvenile Epithelial Corneal Dystrophy Of Meesmann

Mcd

Dystrophy, Corneal, Meesmann
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type

Methylcobalamin Deficiency, Cblg Type

HMAG

Methionine Synthase Deficiency

Methylcobalamin Deficiency Type Cblg

Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism, Cblg Complementation Type

Homocystinuria-Megaloblastic Anemia Cblg Type

Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism Cblg Complementation Type

Methylcobalamin Deficiency Cbl G Type

Homocystinuria Due To Defect In Methylation Cbl G

Cblg

Functional Methionine Synthase Deficiency Type Cblg

Methylcobalamin Deficiency Cblg Type

Arakawa Syndrome 2
Retinitis Pigmentosa 61

RP61

Retinitis Pigmentosa, Type 61
Epithelial And Subepithelial Dystrophy
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10462 PI16 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PI16 RGD RGD:1304760
Mus musculus PI16 MGD MGI:1921366
Felis catus PI16 VGNC VGNC:97555
Macaca mulatta PI16 VGNC VGNC:81497
Canis familiaris PI16 VGNC VGNC:44515
Bos taurus PI16 VGNC VGNC:32853
Others PI16 NCBI
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