CDHR3 - cadherin related family member 3 Gene

中文名称：钙粘蛋白相关家族成员 3

种属: Homo sapiens

同用名: CDH28

基因 ID: 222256 | 基因类型: protein coding

关于 CDHR3

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:105,963,264-106,036,432 (from NCBI)

This gene has 14 transcripts (splice variants), 115 orthologues and 33 paralogues. Biased expression in lung (RPKM 2.7), stomach (RPKM 0.9) and 10 other tissues.

功能概要

预测启用钙粘蛋白结合活性和钙离子结合活性。预计通过质膜细胞粘附分子参与钙依赖性细胞间粘附；细胞形态发生；和细胞-细胞连接组织。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to be involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; and cell-cell junction organization. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CDHR3 基因产物(2)

mRNA	Protein	Name
NM_001301161.2	NP_001288090.1	cadherin-related family member 3 isoform 2
NM_152750.5	NP_689963.2	cadherin-related family member 3 isoform 1 precursor

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in plasma membrane	IDA IDA: 通过直接分析推断	24241537	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CDHR3 蛋白结构

Cadherin

0
200
400
600
800
885 a.a.

蛋白主名

其他名称

cadherin-related family member 3

cadherin-like protein 28

CDHR3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CDHR3	Q6ZTQ4	NEIL2	Homo sapiens	Q969S2	Validated Y2H	32296183
种属内	CDHR3	Q6ZTQ4	CXorf38	Homo sapiens	Q8TB03	Validated Y2H	32296183
种属内	CDHR3	Q6ZTQ4	CLN3	Homo sapiens	Q13286	Y2H Pooling	32814053
种属内	CDHR3	Q6ZTQ4	CLN3	Homo sapiens	Q13286	Validated Y2H	32814053
种属内	CDHR3	Q6ZTQ4	CLN3	Homo sapiens	Q13286	Y2H Array	32814053
种属内	CDHR3	Q6ZTQ4	SRP9	Homo sapiens	P49458	Y2H Pooling	32814053
种属内	CDHR3	Q6ZTQ4	SRP9	Homo sapiens	P49458	Validated Y2H	32814053
种属内	CDHR3	Q6ZTQ4	SRP9	Homo sapiens	P49458	Y2H Array	32814053
种属内	CDHR3	Q6ZTQ4	PARVG	Homo sapiens	Q9HBI0	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Acute Asthma

Childhood-Onset Asthma

Childhood Asthma

Asthma Childhood

Otitis Media

Opsoclonus-Myoclonus Syndrome	OMS
Otitis Media, Susceptibility To	Kinsbourne Syndrome
Otitis Media, Chronic/Recurrent	Come/Rom
Ataxo-Opso-Myoclonus Syndrome	Dancing Eye Syndrome
Dancing Eye-Dancing Feet Syndrome	Oma Syndrome
Opsoclonus Myoclonus Syndrome	Opsoclonus-Myoclonus-Ataxia Syndrome
Poma Syndrome	Paraneoplastic Opsoclonus-Myoclonus
Paraneoplastic Opsoclonus-Myoclonus-Ataxia Syndrome	Opsoclonus Myoclonus
OM	{Otitis Media, Susceptibility To}
Infectious Otitis Media

T2-High Asthma

Type 2 High Endotype

Chronic Asthma

Common Cold

Acute Coryza	Acute Nasopharyngitis
Acute Rhinitis	Acute Viral Rhinopharyngitis
Nasopharyngitis - Acute	Nasopharyngitis, Acute
Rhino-Sinusitis	Rhinosinusitis
Common Colds	Acute Infective Rhinitis
Cold	Coryza
Head Cold	Infective Nasopharyngitis
Rhinopharyngitis	Acute Nasal Catarrh
Infective Rhinitis	Acute Nasopharyngeal Catarrh
Infective Nasopharyngitis Nos	Nasopharyngitis Nos
Epipharyngitis	Mucositis Nos
Inflammatory Disease Of Mucous Membrane	Mucosal Inflammation

Adult-Onset Severe Asthma

Acute Flaccid Myelitis

Bardet-Biedl Syndrome 1

BBS1	Bardet-Biedl Syndrome 1, Modifier Of
Bardet-Biedl Syndrome	BBS
Bardet-Biedl Syndrome, Type 1	Laurence-Moon-Bardet-Biedl Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02345	CDHR3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	CDHR3	VGNC	VGNC:27110
Mus musculus	CDHR3	MGD	MGI:1916014
Canis familiaris	CDHR3	VGNC	VGNC:39039
Rattus norvegicus	CDHR3	RGD	RGD:1591286
Felis catus	CDHR3	VGNC	VGNC:69372

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CDHR3 - cadherin related family member 3 Gene

关于 CDHR3

功能概要

CDHR3 基因产物(2)

CDHR3 蛋白结构

CDHR3 蛋白互作信息

关联疾病

直系同源

热门区域

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CDHR3 - cadherin related family member 3 Gene

关于 CDHR3

功能概要

CDHR3 基因产物(2)

CDHR3 蛋白结构

CDHR3 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z