1. Gene
  2. Hrh4 - histamine receptor H4 Gene

Hrh4 - histamine receptor H4 Gene

中文名称:组胺受体H4

种属: Mus musculus

同用名: H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105

基因 ID: 225192 | 基因类型: protein coding

关于 Hrh4

Chromosome 18: 13,140,047-13,155,939 forward strand.GRCm39:CM001011.3

This gene has 3 transcripts (splice variants), 105 orthologues, 32 paralogues and is associated with 13 phenotypes. Biased expression in testis adult (RPKM 1.) and spleen adult (RPKM .1).

功能概要

该基因编码的蛋白可启动组胺受体活性。预计参与G蛋白偶联受体信号通路;化学突触传递;和炎症反应。预测作用于 G 蛋白偶联受体信号通路的上游或内部。位于膜内。与人类 HRH4(组胺受体 H4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables Histamine Receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; chemical synaptic transmission; and inflammatory response. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in membrane. Orthologous to human HRH4 (Histamine Receptor H4). [provided by Alliance of Genome Resources, Apr 2022]

Hrh4 基因产物(1)

mRNA Protein Name
NM_153087.2 NP_694727.1 histamine H4 receptor

Hrh4 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (15 - 375)

7tm_GPCRs

7tm_GPCRs: cd14964 (17 - 41)

7tm_GPCRs

7tm_GPCRs: cd14964 (50 - 72)

7tm_GPCRs

7tm_GPCRs: cd14964 (87 - 109)

7tm_GPCRs

7tm_GPCRs: cd14964 (133 - 149)

7tm_GPCRs

7tm_GPCRs: cd14964 (173 - 196)

7tm_GPCRs

7tm_GPCRs: cd14964 (303 - 325)

7tm_GPCRs

7tm_GPCRs: cd14964 (338 - 363)

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  • 391 a.a.
蛋白主名 其他名称

histamine H4 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hrh4 NCBI NCBI:59340