2. Gene
  3. Gpbar1 - G protein-coupled bile acid receptor 1 Gene

Gpbar1 - G protein-coupled bile acid receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联胆汁酸受体 1

种属: Mus musculus

同用名: BG37; GPCR; TGR5; M-BAR; GPR131

基因 ID: 227289 | 基因类型: protein coding

关于 Gpbar1

Chromosome 1: 74,317,709-74,318,783 forward strand.GRCm39:CM000994.3

This gene has 1 transcript (splice variant), 75 orthologues and is associated with 24 phenotypes.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联胆汁酸受体活性。参与调节双细胞紧密连接装配。预测位于细胞质和质膜。预计是受体复合体的一部分。在肠道和雄性生殖腺或器官中表达。与人类 GPBAR1（G 蛋白偶联胆汁酸受体 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled bile acid receptor activity. Involved in regulation of bicellular tight junction assembly. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of receptor complex. Is expressed in gut and male reproductive gland or organ. Orthologous to human GPBAR1 (G protein-coupled Bile Acid Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Gpbar1 基因产物(1)

mRNA Protein Name
NM_174985.2 NP_778150.1 G-protein coupled bile acid receptor 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of bicellular tight junction assembly IMP
IMP: 通过突变表型推断
22046243 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Gpbar1 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (26 - 282)

7tm_GPCRs

7tm_GPCRs: cd14964 (49 - 70)

7tm_GPCRs

7tm_GPCRs: cd14964 (84 - 106)

7tm_GPCRs

7tm_GPCRs: cd14964 (124 - 140)

7tm_GPCRs

7tm_GPCRs: cd14964 (160 - 183)

7tm_GPCRs

7tm_GPCRs: cd14964 (221 - 243)

7tm_GPCRs

7tm_GPCRs: cd14964 (257 - 282)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
蛋白主名 其他名称

G-protein coupled bile acid receptor 1

G protein-coupled receptor TGR5

membrane bile acid receptor

membrane-type receptor for bile acids

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101274 BAR501 Agonist ≥98.0% 否
HY-101273 BAR502 Agonist 99.53% 否
HY-147086 CAY10789 99.84% 否
HY-145234 GPBAR1-IN-3 / 否
HY-107612 GPBAR-A Agonist / 否
HY-146453 TGR5 Receptor Agonist 3 Agonist / 否
HY-RS05622 GPBAR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05623 Gpbar1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05624 Gpbar1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-165155 CysLT1 receptor antagonist-1 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpbar1 NCBI NCBI:151306
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