DLGAP4 - DLG associated protein 4 Gene

中文名称：DLG 相关蛋白 4

种属: Homo sapiens

同用名: DAP4; DLP4; DAP-4; SAPAP4; SAPAP-4

关于 DLGAP4

功能概要

该基因的产物是在神经元细胞的突触后密度发现的膜相关鸟苷酸激酶。它是一种信号分子，可以与钾通道和受体以及其他信号分子相互作用。由该基因编码的蛋白质可以通过其鸟苷酸激酶结构域与 PSD-95 相互作用，并可能参与突触后密度区域的 PSD-95 聚类。编码的蛋白质是已发现的至少四种相似蛋白质之一。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as Other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]