2. Gene
  3. Trib3 - tribbles pseudokinase 3 Gene

Trib3 - tribbles pseudokinase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nipk; SINK; Trb3; Ifld2; SKIP3; TRB-3

基因 ID: 228775 | 基因类型: protein coding

关于 Trib3

功能概要

Enables Enzyme binding activity; transcription corepressor activity; and ubiquitin-protein transferase regulator activity. Involved in several processes, including negative regulation of fat cell differentiation; negative regulation of fatty acid biosynthetic process; and regulation of protein modification process. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart; and retina. Orthologous to human TRIB3 (tribbles pseudokinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Trib3 基因产物(1)

mRNA Protein Name
NM_175093.2 NP_780302.2 tribbles homolog 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
16794074 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12749859 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
12791994 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
12749859 MGI
enables ubiquitin protein ligase binding IDA
IDA: 通过直接分析推断
20410507 MGI
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
16794074 MGI
enables ubiquitin-protein transferase regulator activity IDA
IDA: 通过直接分析推断
20410507 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
12791994 MGI
involved in negative regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
17576771 MGI
involved in negative regulation of fatty acid biosynthetic process IMP
IMP: 通过突变表型推断
16794074 MGI
involved in negative regulation of protein kinase activity IDA
IDA: 通过直接分析推断
12791994 MGI
involved in positive regulation of protein binding IDA
IDA: 通过直接分析推断
16794074 MGI
involved in positive regulation of ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
16794074 MGI
involved in regulation of D-glucose transmembrane transport IDA
IDA: 通过直接分析推断
12791994 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12749859 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tribbles homolog 3

induced in fatty liver dystrophy 2

neuronal cell death-inducible putative kinase

Trib3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Trib3 Q8K4K2 Akt1 Mus musculus P31750
Y2H
12791994
种属内
Trib3 Q8K4K2 Akt1 Mus musculus P31750
Anti Tag CoIP
12791994
种属内
Trib3 Q8K4K2 Akt1 Mus musculus P31750
Pull Down
12791994
种属内
Trib3 Q8K4K2 Atf4 Mus musculus Q06507
Anti Tag CoIP
12749859
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16261 Trib3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS15017 TRIB3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trib3 NCBI NCBI:57761
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