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  2. ZC3H13 - zinc finger CCCH-type containing 13 Gene

ZC3H13 - zinc finger CCCH-type containing 13 Gene

中文名称:含锌指 CCCH 型 13

种属: Homo sapiens

同用名: Xio; KIAA0853

基因 ID: 23091 | 基因类型: protein coding

关于 ZC3H13

Cytogenetic location: 13q14.13 Genomic coordinates (GRCh38): 13:45,954,465-46,052,746 (from NCBI)

This gene has 6 transcripts (splice variants) and 158 orthologues. Ubiquitous expression in brain (RPKM 10.7), thyroid (RPKM 9.2) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与 mRNA 甲基化。位于核斑点。 RNA N6-甲基腺苷甲基转移酶复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables RNA binding activity. Involved in mRNA methylation. Located in nuclear speck. Part of RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H13 基因产物(15)

mRNA Protein Name
NM_001076788.2 NP_001070256.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330564.2 NP_001317493.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330565.2 NP_001317494.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330566.2 NP_001317495.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330567.2 NP_001317496.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382206.1 NP_001369135.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382207.1 NP_001369136.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382208.1 NP_001369137.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382209.1 NP_001369138.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382210.1 NP_001369139.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382211.1 NP_001369140.1 zinc finger CCCH domain-containing protein 13 isoform 4
NM_001382212.1 NP_001369141.1 zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382213.1 NP_001369142.1 zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382214.1 NP_001369143.1 zinc finger CCCH domain-containing protein 13 isoform 6
NM_015070.6 NP_055885.3 zinc finger CCCH domain-containing protein 13 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20195357 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA processing IMP
IMP: 通过突变表型推断
29507755 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: 通过直接分析推断
29507755 GOA
part of RNA N6-methyladenosine methyltransferase complex IPI
IPI: 通过物理相互作用推断
29507755 GOA
located in nuclear speck IDA
IDA: 通过直接分析推断
24100041 GOA
located in nucleoplasm IDA
IDA: 通过直接分析推断
24100041 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ZC3H13 蛋白结构

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (42 - 63)

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  • 1668 a.a.
蛋白主名 其他名称

zinc finger CCCH domain-containing protein 13

ZC3H13 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ZC3H13 Q5T200 SCHIP1 Homo sapiens P0DPB3
Display Tech
20195357
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Uterine Corpus Endometrial Carcinoma
Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZC3H13 VGNC VGNC:37101
Rattus norvegicus ZC3H13 RGD RGD:1307729
Canis familiaris ZC3H13 VGNC VGNC:48554
Macaca mulatta ZC3H13 VGNC VGNC:79248
Felis catus ZC3H13 VGNC VGNC:67183
Mus musculus ZC3H13 MGD MGI:1914552