1. Gene
  2. RRS1 - ribosome biogenesis regulator 1 homolog Gene

RRS1 - ribosome biogenesis regulator 1 homolog Gene

中文名称:核糖体生物发生调节因子 1 同系物

种属: Homo sapiens

基因 ID: 23212 | 基因类型: protein coding

关于 RRS1

Cytogenetic location: 8q13.1 Genomic coordinates (GRCh38): 8:66,429,014-66,430,733 (from NCBI)

This gene has 1 transcript (splice variant) and 174 orthologues.

功能概要

启用 5S rRNA 结合活性。参与多个过程,包括有丝分裂中期板大会;蛋白质定位于核仁;和核糖体大亚基组装。位于浓缩核染色体;核仁;和核质。 [由基因组资源联盟提供,2022 年 4 月]

Enables 5S rRNA binding activity. Involved in several processes, including mitotic metaphase plate congression; protein localization to nucleolus; and ribosomal large subunit assembly. Located in condensed nuclear chromosome; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RRS1 基因产物(1)

mRNA Protein Name
NM_015169.4 NP_055984.1 ribosome biogenesis regulatory protein homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5S rRNA binding IDA
IDA: 通过直接分析推断
24120868 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitotic metaphase chromosome alignment IMP
IMP: 通过突变表型推断
19465021 GOA
involved in protein localization to nucleolus IMP
IMP: 通过突变表型推断
24120868 GOA
involved in regulation of signal transduction by p53 class mediator IMP
IMP: 通过突变表型推断
24120868 GOA
involved in ribosomal large subunit assembly IMP
IMP: 通过突变表型推断
24120868 GOA
involved in ribosomal large subunit biogenesis IMP
IMP: 通过突变表型推断
24120868 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in condensed nuclear chromosome IDA
IDA: 通过直接分析推断
19465021 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
19465021 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RRS1 蛋白结构

RRS1

RRS1: Ribosome biogenesis regulatory protein (RRS1) (31 - 193)

  • 0
  • 100
  • 200
  • 300
  • 365 a.a.
蛋白主名 其他名称

ribosome biogenesis regulatory protein homolog

RRS1 ribosome biogenesis regulator homolog

RRS1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RRS1 Q15050 RPF2 Homo sapiens Q9H7B2
Anti Tag CoIP
28514442
种属内
RRS1 Q15050 RPF2 Homo sapiens Q9H7B2
Anti Tag CoIP
33961781
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Validated Y2H
25416956
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Validated Y2H
32296183
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Y2H Array
25416956
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Y2H Array
32296183
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Y2H Prey Pooling
25416956
种属内
RRS1 Q15050 APPBP2 Homo sapiens Q92624
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Flinders Island Spotted Fever

Fisf

Thai Tick Typhus

Robinow Syndrome, Autosomal Recessive 1

Robinow Syndrome, Autosomal Recessive

Autosomal Recessive Robinow Syndrome

Covesdem Syndrome

RRS1

Costovertebral Segmentation Defect-Mesomelia Syndrome

Rrs

Costovertebral Segmentation Defect With Mesomelia, Formerly

Covesdem Syndrome, Formerly

Costovertebral Segmentation Defect With Mesomelia

Robinow Syndrome Autosomal Recessive With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals

Robinow Syndrome Autosomal Recessive With Brachy-Syn-Polydactyly

Robinow Syndrome, Autosomal Recessive, With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals

Robinow Syndrome, Autosomal Recessive, With Brachy-Syn-Polydactyly

Robinow, Autosomal Recessive Syndrome, Type 1

Robinow Syndrome, Autosomal Dominant 3

Autosomal Dominant Robinow Syndrome 3

DRS3

Robinow, Autosomal Dominant Syndrome, Type 3

Robinow Syndrome

Acral Dysostosis With Facial And Genital Abnormalities

Fetal Face Syndrome

Robinow Dwarfism

Mesomelic Dwarfism-Small Genitalia Syndrome

Robinow-Silverman-Smith Syndrome

Costovertebral Segmentation Defect With Mesomelia

Covesdem Syndrome

Robinow'S Syndrome

Robinow-Silverman Syndrome

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RRS1 RGD RGD:1311403
Macaca mulatta RRS1 VGNC VGNC:77035
Bos taurus RRS1 VGNC VGNC:34173
Canis familiaris RRS1 VGNC VGNC:45768
Mus musculus RRS1 MGD MGI:1929721
Felis catus RRS1 VGNC VGNC:64784