2. Gene
  3. VPS8 - VPS8 subunit of CORVET complex Gene

VPS8 - VPS8 subunit of CORVET complex Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CORVET 复合体的 VPS8 亚基

种属: Homo sapiens

同用名: KIAA0804

基因 ID: 23355 | 基因类型: protein coding

关于 VPS8

Cytogenetic location: 3q27.2 Genomic coordinates (GRCh38): 3:184,812,166-185,052,614 (from NCBI)

This gene has 28 transcripts (splice variants), 215 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 8.2), brain (RPKM 7.7) and 25 other tissues.

功能概要

预测可启用金属离子结合活性。参与内体囊泡融合。位于早期内体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable metal ion binding activity. Involved in endosomal vesicle fusion. Located in early endosome. [provided by Alliance of Genome Resources, Apr 2022]

VPS8 基因产物(9)

mRNA Protein Name
NM_001009921.3 NP_001009921.1 vacuolar protein sorting-associated protein 8 homolog isoform a
NM_001349292.2 NP_001336221.1 vacuolar protein sorting-associated protein 8 homolog isoform a
NM_001349293.2 NP_001336222.1 vacuolar protein sorting-associated protein 8 homolog isoform a
NM_001349294.2 NP_001336223.1 vacuolar protein sorting-associated protein 8 homolog isoform a
NM_001349295.1 NP_001336224.1 vacuolar protein sorting-associated protein 8 homolog isoform a
NM_001349296.2 NP_001336225.1 vacuolar protein sorting-associated protein 8 homolog isoform c
NM_001349297.2 NP_001336226.1 vacuolar protein sorting-associated protein 8 homolog isoform d
NM_001349298.2 NP_001336227.1 vacuolar protein sorting-associated protein 8 homolog isoform e
NM_015303.4 NP_056118.2 vacuolar protein sorting-associated protein 8 homolog isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25266290 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endosomal vesicle fusion IMP
IMP: 通过突变表型推断
25266290 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in early endosome IDA
IDA: 通过直接分析推断
25266290 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VPS8 蛋白结构

Vps8

Vps8: Golgi CORVET complex core vacuolar protein 8 (612 - 796)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1428 a.a.
蛋白主名 其他名称

vacuolar protein sorting-associated protein 8 homolog

VPS8, CORVET complex subunit

VPS8 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
VPS8 Q8N3P4 TGFBRAP1 Homo sapiens Q8WUH2
Anti Tag CoIP
35271311
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ritscher-Schinzel Syndrome 1

3c Syndrome

Craniocerebellocardiac Dysplasia

RTSC1

Dandy-Walker-Like Malformation With Atrioventricular Septal Defect

Dandy-Walker Like Malformation With Atrioventricular Septal Defect

Cranio-Cerebello-Cardiac Dysplasia

Dandy-Walker-Like Malformation With Asd

Ritscher Schinzel Syndrome

Ritscher-Schinzel Cranio-Cerebello-Cardiac Syndrome

Ritscher-Schinzel Syndrome

3c
Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15701 VPS8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus VPS8 RGD RGD:1309443
Felis catus VPS8 VGNC VGNC:97683
Macaca mulatta VPS8 VGNC VGNC:79779
Mus musculus VPS8 MGD MGI:2146407
Bos taurus VPS8 VGNC VGNC:36832
Canis familiaris VPS8 VGNC VGNC:48300
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