2. Gene
  3. TSPAN15 - tetraspanin 15 Gene

TSPAN15 - tetraspanin 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：四跨膜蛋白 15

种属: Homo sapiens

同用名: NET7; NET-7; TM4SF15; 2700063A19Rik

基因 ID: 23555 | 基因类型: protein coding

关于 TSPAN15

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:69,451,465-69,549,508 (from NCBI)

This gene has 8 transcripts (splice variants), 204 orthologues and 32 paralogues. Broad expression in fat (RPKM 7.7), stomach (RPKM 7.1) and 21 other tissues.

功能概要

由该基因编码的蛋白质是跨膜 4 超家族的成员，也称为四跨膜蛋白家族。这些成员中的大多数是细胞表面蛋白，其特征在于存在四个疏水结构域。这些蛋白质介导在细胞发育、活化、生长和运动的调节中起作用的信号转导事件。已发现该基因使用替代聚腺苷酸化位点。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

TSPAN15 基因产物(2)

mRNA Protein Name
NM_001351263.2 NP_001338192.1 tetraspanin-15 isoform 2
NM_012339.5 NP_036471.1 tetraspanin-15 isoform 1

TSPAN15 蛋白结构

Tetraspannin

Tetraspannin: Tetraspanin family (20 - 255)

  • 0
  • 100
  • 200
  • 294 a.a.
蛋白主名 其他名称

tetraspanin-15

tetraspan NET-7

TSPAN15 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TSPAN15 O95858 STRIT1 Homo sapiens P0DN84
Validated Y2H
32296183
Intra TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Bait CoIP
26686862
Intra TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Tag CoIP
26686862
Intra TSPAN15 O95858 ADAM10 Homo sapiens O14672
Anti Tag CoIP
33961781
Intra TSPAN15 O95858 GYPC Homo sapiens P04921
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Femoral Vein Thrombophlebitis

Phlebitis And Thrombophlebitis Of Femoral Vein

Thrombophlebitis Of The Femoral Vein

Thrombophlebitis Of Deep Femoral Vein
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15163 TSPAN15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TSPAN15 VGNC VGNC:36430
Felis catus TSPAN15 VGNC VGNC:66627
Rattus norvegicus TSPAN15 RGD RGD:1588304
Canis familiaris TSPAN15 VGNC VGNC:47915
Mus musculus TSPAN15 MGD MGI:1917673
Macaca mulatta TSPAN15 VGNC VGNC:79385
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