ZIM2 - zinc finger imprinted 2 Gene

中文名称：锌指印迹 2

种属: Homo sapiens

同用名: ZNF656

关于 ZIM2

功能概要

在人类中，ZIM2 和 PEG3 (GeneID:5178) 是两个不同的基因，它们共享一组 5' 外显子并具有共同的启动子，并且这两个基因都是父系表达的。选择性剪接事件将共享外显子与 ZIM2 独有的其余 4 个外显子或与 PEG3 独有的其余 2 个外显子连接起来。这与小鼠和牛形成对比，其中 ZIM2 和 PEG3 基因不共享共同的外显子，并且 ZIM2 的印记状态在哺乳动物中也不保守。已为人类 ZIM2 基因发现编码相同蛋白质的其他 5' 可变剪接转录本。[RefSeq 提供，2010 年 10 月]

In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]