Nox1 - NADPH oxidase 1 Gene

中文名称：NADPH 氧化酶1

种属: Mus musculus

同用名: MOX1; NOH1; NOH-1; NOX1a; Nox-1; GP91-2; NOX1alpha

关于 Nox1

功能概要

该基因编码 NADPH 氧化酶的一个亚基，它是一种膜结合的多亚基蛋白。这种复合物催化电子从 NADPH 转移到分子氧以产生超氧化物或过氧化氢，并可能在抗菌杀灭和细胞信号传导中发挥作用。这种蛋白质结合其他亚基以产生超氧化物。在小鼠中，这种酶的缺乏可能与血压变化有关。 [RefSeq 提供，2013 年 6 月]

This gene encodes a subunit of the NADPH Oxidase enzyme, which is a membrane-bound, multisubunit protein. This complex catalyzes the transfer of electrons from NADPH to molecular oxygen to produce superoxide or hydrogen peroxide and may have a role in antimicrobial killing and cell signaling. This protein binds other subunits in order to produce superoxide. In mouse, deficiency of this Enzyme may be associated with changes in blood pressure. [provided by RefSeq, Jun 2013]