2. Gene
  3. EID1 - EP300 interacting inhibitor of differentiation 1 Gene

EID1 - EP300 interacting inhibitor of differentiation 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：EP300 相互作用的分化抑制因子 1

种属: Homo sapiens

同用名: CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

基因 ID: 23741 | 基因类型: protein coding

关于 EID1

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:48,878,134-48,880,173 (from NCBI)

This gene has 2 transcripts (splice variants), 88 orthologues and 2 paralogues.

功能概要

启用组蛋白乙酰转移酶结合活性和组蛋白乙酰转移酶调节剂活性。参与细胞分化和转录负调控，DNA 模板化。在 RNA 聚合酶 II 的转录负调节上游或负调节内起作用。位于细胞质核糖核蛋白颗粒和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables Histone Acetyltransferase binding activity and Histone Acetyltransferase regulator activity. Involved in cell differentiation and negative regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasmic ribonucleoprotein granule and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EID1 基因产物(1)

mRNA Protein Name
NM_014335.3 NP_055150.1 EP300-interacting inhibitor of differentiation 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone acetyltransferase binding IDA
IDA: 通过直接分析推断
11073990 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
11073990 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell differentiation IDA
IDA: 通过直接分析推断
11073989 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11073990 GOA
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11073990 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

EP300-interacting inhibitor of differentiation 1

21 kDa pRb-associated protein

EID1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
EID1 Q9Y6B2 Ndn Mus musculus P25233
Anti Bait CoIP
18557765
种属间
EID1 Q9Y6B2 Ndn Mus musculus P25233
Anti Tag CoIP
18557765
种属内
EID1 Q9Y6B2 FBXO21 Homo sapiens O94952
Anti Tag CoIP
26085330
种属内
EID1 Q9Y6B2 FBXO21 Homo sapiens O94952
Anti Tag CoIP
33961781
种属内
EID1 Q9Y6B2 NDN Homo sapiens Q99608
Anti Tag CoIP
32529326
种属内
EID1 Q9Y6B2 NDN Homo sapiens Q99608
Anti Tag CoIP
21364888
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms
Hyperhidrosis, Gustatory

Frey Syndrome

Gustatory Sweating

Auriculotemporal Nerve Syndrome

Gustatory Hyperhidrosis

Frey'S Syndrome

Sweating, Gustatory

HYPRG

Baillarger Syndrome

Hyperhidrosis Gustatory

Auriculotemporal Syndrome
Prader-Willi Syndrome

Prader-Labhart-Willi Syndrome

PWS

Willi-Prader Syndrome

Prader-Willi Syndrome Due To Translocation

Prader-Willi Syndrome Due To Imprinting Mutation

Prader-Willi Syndrome Due To Maternal Uniparental Disomy Of Chromosome 15

Prader Willi Syndrome

Upd(15)Mat
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04234 EID1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris EID1 VGNC VGNC:40252
Rattus norvegicus EID1 RGD RGD:1562702
Mus musculus EID1 MGD MGI:1889651
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z