1. Gene
  2. Agr2 - anterior gradient 2 Gene

Agr2 - anterior gradient 2 Gene

种属: Mus musculus

同用名: Agr2h; Gob-4; HAG-2; XAG-2; mAG-2

基因 ID: 23795 | 基因类型: protein coding

关于 Agr2

功能概要

Predicted to enable dystroglycan binding activity; epidermal growth factor receptor binding activity; and identical protein binding activity. Involved in digestive tract morphogenesis; mucus secretion; and positive regulation of developmental growth. Acts upstream of or within lung goblet cell differentiation. Located in endoplasmic reticulum. Is expressed in several structures, including eye; genitourinary system; gut; liver; and lung. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member). [provided by Alliance of Genome Resources, Apr 2022]

Agr2 基因产物(1)

mRNA Protein Name
NM_011783.2 NP_035913.1 anterior gradient protein 2 homolog precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31040128 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in digestive tract morphogenesis IMP
IMP: 通过突变表型推断
25666625 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
31040128 MGI
acts upstream of or within lung goblet cell differentiation IDA
IDA: 通过直接分析推断
22675208 MGI
acts upstream of or within mucus secretion IMP
IMP: 通过突变表型推断
19359471 MGI
involved in mucus secretion IMP
IMP: 通过突变表型推断
19359471 MGI
involved in positive regulation of developmental growth IMP
IMP: 通过突变表型推断
25666625 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
19359471 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

anterior gradient protein 2 homolog

AG-2

anterior gradient 2 homolog

protein Gob-4

secreted cement gland protein XAG-2 homolog

重组 Agr2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78771 AG-2 Protein, Mouse (HEK293, His) O88312 (K21-L175) ≥95%
HY-P701076 AG-2 Protein, Mouse (His) NP_035913.1 (K21-L175) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Agr2 NCBI NCBI:10551