1. Gene
  2. Rspo2 - R-spondin 2 Gene

Rspo2 - R-spondin 2 Gene

种属: Mus musculus

同用名: ftls; D430027K22; 2610028F08Rik

基因 ID: 239405 | 基因类型: protein coding

关于 Rspo2

功能概要

Enables heparin binding activity. Acts upstream of or within several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Located in cell surface and extracellular region. Is expressed in several structures, including brain; jaw; limb bud; pelvic urethra; and sensory organ. Human ortholog(s) of this gene implicated in tetraamelia syndrome 2. Orthologous to human RSPO2 (R-spondin 2). [provided by Alliance of Genome Resources, Apr 2022]

Rspo2 基因产物(3)

mRNA Protein Name
NM_001357956.1 NP_001344885.1 R-spondin-2 isoform 2 precursor
NM_001357957.1 NP_001344886.1 R-spondin-2 isoform 1 precursor
NM_172815.3 NP_766403.1 R-spondin-2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
16543246 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone mineralization IGI
IGI: 通过遗传相互作用推断
19213727 MGI
acts upstream of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
19213727 MGI
acts upstream of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within dopaminergic neuron differentiation IMP
IMP: 通过突变表型推断
24066094 MGI
acts upstream of or within embryonic forelimb morphogenesis IGI
IGI: 通过遗传相互作用推断
18256198 MGI
acts upstream of or within embryonic forelimb morphogenesis IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within embryonic hindlimb morphogenesis IGI
IGI: 通过遗传相互作用推断
18256198 MGI
acts upstream of or within embryonic hindlimb morphogenesis IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within epithelial tube branching involved in lung morphogenesis IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within lung growth IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within negative regulation of odontogenesis of dentin-containing tooth IMP
IMP: 通过突变表型推断
24616052 MGI
acts upstream of or within osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
19213727 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
18256198 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
18256198 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
18256198 MGI
acts upstream of or within trachea cartilage morphogenesis IGI
IGI: 通过遗传相互作用推断
18256198 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
18256198 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
16543246 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

R-spondin-2

R-spondin 2 homolog

cristin-2

cysteine-rich and single thrombospondin domain-containing protein 2

mCristin-2

roof plate-specific spondin-2

重组 Rspo2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76013 RSPO2/R-spondin-2 Protein, Mouse (Fc) Q8BFU0 (N24-G205) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rspo2 NCBI NCBI:340419