2. Gene
  3. Ago2 - argonaute RISC catalytic subunit 2 Gene

Ago2 - argonaute RISC catalytic subunit 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Eif2c2; Gerp95; Gm10365; mKIAA4215; 1110029L17Rik; 2310051F07Rik

基因 ID: 239528 | 基因类型: protein coding

关于 Ago2

功能概要

Enables endoribonuclease activity; mRNA binding activity; and miRNA binding activity. Involved in regulation of gene expression. Acts upstream of or within RNA metabolic process; positive regulation of gene expression; and post-embryonic development. Located in several cellular components, including P-body; cytosol; and dendrite. Part of RISC complex and RISC-loading complex. Is expressed in several structures, including central nervous system; early embryo; lung; sensory organ; and tooth. Orthologous to human AGO2 (argonaute RISC catalytic component 2). [provided by Alliance of Genome Resources, Apr 2022]

Ago2 基因产物(1)

mRNA Protein Name
NM_153178.5 NP_694818.3 protein argonaute-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
19536157 MGI
enables RNA endonuclease activity IDA
IDA: 通过直接分析推断
20424607 MGI
enables mRNA binding IDA
IDA: 通过直接分析推断
20975942 MGI
enables miRNA binding IDA
IDA: 通过直接分析推断
23185045 MGI
enables miRNA binding IMP
IMP: 通过突变表型推断
22503104 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12526743 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within miRNA metabolic process IDA
IDA: 通过直接分析推断
22053081 MGI
acts upstream of or within miRNA processing IMP
IMP: 通过突变表型推断
20424607 MGI
involved in miRNA-mediated gene silencing by mRNA destabilization IDA
IDA: 通过直接分析推断
16357216 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
22053081 MGI
involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
IMP: 通过突变表型推断
19716330 MGI
involved in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IMP
IMP: 通过突变表型推断
19716330 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
20424607 MGI
involved in pre-miRNA processing IDA
IDA: 通过直接分析推断
16357216 MGI
involved in regulatory ncRNA-mediated gene silencing IMP
IMP: 通过突变表型推断
19716330 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in P-body IDA
IDA: 通过直接分析推断
19898466 MGI
part of RISC complex IDA
IDA: 通过直接分析推断
16357216 MGI
part of RISC-loading complex IDA
IDA: 通过直接分析推断
16357216 MGI
part of RISC-loading complex IPI
IPI: 通过物理相互作用推断
20211135 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22053081 MGI
located in dendrite IDA
IDA: 通过直接分析推断
22022532 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22053081 MGI
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
24427314 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein argonaute-2

Piwi/Argonaute family protein meIF2C2

argonaute 2

argonaute RISC catalytic component 2

eukaryotic translation initiation factor 2C, 2

重组 Ago2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74423 AGO2/Argonaute-2 Protein, Mouse (sf9, His) Q8CJG0 (M1-A860) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-119024 BCI-137 99.55% 否
HY-RS00453 AGO2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ago2 NCBI NCBI:27161
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z