2. Gene
  3. Dact2 - dishevelled-binding antagonist of beta-catenin 2 Gene

Dact2 - dishevelled-binding antagonist of beta-catenin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dpr2; Frd2; dapper2; A630024E20; 2900084M21Rik

基因 ID: 240025 | 基因类型: protein coding

关于 Dact2

功能概要

Enables several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and negative regulation of nodal signaling pathway. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and umbilical vein. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2). [provided by Alliance of Genome Resources, Apr 2022]

Dact2 基因产物(1)

mRNA Protein Name
NM_172826.3 NP_766414.3 dapper homolog 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IDA
IDA: 通过直接分析推断
21718540 MGI
enables delta-catenin binding IDA
IDA: 通过直接分析推断
21718540 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21718540 MGI
enables protein kinase A binding IDA
IDA: 通过直接分析推断
21718540 MGI
enables protein kinase C binding IDA
IDA: 通过直接分析推断
21718540 MGI
enables transcription factor binding IDA
IDA: 通过直接分析推断
21718540 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial cell morphogenesis IMP
IMP: 通过突变表型推断
20685821 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
24029230 MGI
involved in inner medullary collecting duct development IMP
IMP: 通过突变表型推断
20685821 MGI
involved in negative regulation of cell adhesion IMP
IMP: 通过突变表型推断
18716284 MGI
involved in negative regulation of nodal signaling pathway IDA
IDA: 通过直接分析推断
17197390 MGI
involved in negative regulation of nodal signaling pathway IMP
IMP: 通过突变表型推断
18716284 MGI
NOT involved in regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
17197390 MGI
involved in skin development IMP
IMP: 通过突变表型推断
18716284 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dapper homolog 2

dapper antagonist of catenin 2

dapper homolog 2, antagonist of beta-catenin

dapper, antagonist of beta-catenin, homolog 2

mDpr2

Dact2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Dact2 Q7TN08 Dact3 Mus musculus Q0PHV7
Anti Tag CoIP
21718540
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03516 DACT2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dact2 NCBI NCBI:168002
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