1. Gene
  2. Sigirr - single immunoglobulin and toll-interleukin 1 receptor (TIR) domain Gene

Sigirr - single immunoglobulin and toll-interleukin 1 receptor (TIR) domain Gene

种属: Mus musculus

同用名: TIR8

基因 ID: 24058 | 基因类型: protein coding

关于 Sigirr

功能概要

Involved in acute-phase response; negative regulation of chemokine production; and negative regulation of cytokine-mediated signaling pathway. Predicted to be located in membrane. Is expressed in genitourinary system. Orthologous to human SIGIRR (single Ig and TIR domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Sigirr 基因产物(2)

mRNA Protein Name
NM_001355055.1 NP_001341984.1 single Ig IL-1-related receptor
NM_023059.3 NP_075546.2 single Ig IL-1-related receptor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IMP
IMP: 通过突变表型推断
12925853 MGI
involved in negative regulation of chemokine production IMP
IMP: 通过突变表型推断
12925853 MGI
involved in negative regulation of cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
12925853 MGI
involved in negative regulation of interleukin-1-mediated signaling pathway IMP
IMP: 通过突变表型推断
12925853 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

single Ig IL-1-related receptor

single Ig IL-1 receptor related protein

single Ig IL-1R-related molecule

single Ig IL-1R-related protein

single immunoglobulin domain-containing IL1R-related protein

toll/interleukin-1 receptor 8

重组 Sigirr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74547 SIGIRR Protein, Mouse (HEK293, His) Q9JLZ8 (M1-H117) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sigirr NCBI NCBI:59307